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1. (WO2002026757) MODULATION OF IMMUNOSTIMULATORY ACTIVITY OF IMMUNOSTIMULATORY OLIGONUCLEOTIDE ANALOGS BY POSITIONAL CHEMICAL CHANGES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026757    International Application No.:    PCT/US2001/030137
Publication Date: 04.04.2002 International Filing Date: 26.09.2001
Chapter 2 Demand Filed:    04.04.2002    
IPC:
A61K 31/7088 (2006.01), A61K 31/7115 (2006.01), C07H 21/00 (2006.01), C12N 15/11 (2006.01)
Applicants: HYBRIDON, INC. [US/US]; 345 Vassar Street Cambridge, MA 02139 (US)
Inventors: KANDIMALLA, Ekambar, R.; (US).
ZHAO, Quiyan; (US).
YU, Dong; (US).
AGRAWAL, Sudhir; (US)
Agent: WAYNE A. Keown, Ph.D.; Law Offices of A.Keown 500 West Cummings Park, Suite 2900 Woburn, MA 01801 USA (US)
Priority Data:
60/235,452 26.09.2000 US
60/235,453 26.09.2000 US
09/712,898 15.11.2000 US
Title (EN) MODULATION OF IMMUNOSTIMULATORY ACTIVITY OF IMMUNOSTIMULATORY OLIGONUCLEOTIDE ANALOGS BY POSITIONAL CHEMICAL CHANGES
(FR) MODULATION DE L'ACTIVITE IMMUNOSTIMULATRICE D'ANALOGUES OLIGONUCLEOTIDIQUES IMMUNOSTIMULATEURS PAR DES MODIFICATIONS CHIMIQUES DE POSITION
Abstract: front page image
(EN)The invention relates to the therapeutic use of oligonucleotides or oligonucleotide analogs as immunostimulatory agents in immunotherapy applications. The invention provides methods for enhancing the immune response caused by immunostimulatory oligonucleotide compounds.
(FR)L'invention concerne l'utilisation thérapeutique d'oligonucléotides ou d'analogues oligonucléotidiques comme agents immunostimulateurs dans des applications d'immunothérapie ; et des procédés visant à renforcer la réaction immunitaire provoquée par des composés oligonuléotidiques immunostimulateurs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)