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1. WO2002026743 - NOVEL PYRIDAZINE COMPOUNDS FOR THE TREATMENT OF DIABETES

Publication Number WO/2002/026743
Publication Date 04.04.2002
International Application No. PCT/SE2001/002097
International Filing Date 26.09.2001
Chapter 2 Demand Filed 22.04.2002
IPC
C07D 237/26 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
237Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26condensed with carbocyclic rings or ring systems
C07D 237/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
237Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26condensed with carbocyclic rings or ring systems
28Cinnolines
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 491/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
C07D 237/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
237Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26condensed with carbocyclic rings or ring systems
C07D 237/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
237Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26condensed with carbocyclic rings or ring systems
28Cinnolines
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 491/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • BIOVITRUM AB [SE]/[SE] (AllExceptUS)
  • BARKER, Emma [GB]/[GB] (UsOnly)
  • BYSTRÖM, Styrbjörn [SE]/[SE] (UsOnly)
  • DESARBRE, Eric [FR]/[SE] (UsOnly)
  • DUFFY, James [GB]/[GB] (UsOnly)
  • JAMES, Stephen [GB]/[SE] (UsOnly)
  • LILJEBRIS, Charlotta [SE]/[SE] (UsOnly)
  • MARTINSSON, Jessica [SE]/[SE] (UsOnly)
Inventors
  • BARKER, Emma
  • BYSTRÖM, Styrbjörn
  • DESARBRE, Eric
  • DUFFY, James
  • JAMES, Stephen
  • LILJEBRIS, Charlotta
  • MARTINSSON, Jessica
Agents
  • HÖGLUND, Lars
Priority Data
0003436-326.09.2000SE
0101933-001.06.2001SE
60/239,32710.10.2000US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL PYRIDAZINE COMPOUNDS FOR THE TREATMENT OF DIABETES
(FR) NOUVEAUX COMPOSES DE PYRIDAZINE POUR LE TRAITEMENT DE DIABETES
Abstract
(EN) The present invention is directed to novel pyridazine compounds of the formula (I) as well as pharmaceutically and pharmaceutically acceptable salts, and hydrates thereof; to a process for their preparation, their use and pharmaceutical compositions comprising said novel compounds. These novel compounds are useful in therapy, particularly for the treatment of type 2 diabetes mellitus.
(FR) La présente invention concerne de nouveaux composés de pyridazine de la formule (I) ainsi que des sels pharmaceutiquement et pharmacologiquement acceptables, et leurs hydrates. L'invention concerne également leur procédé de préparation, leur utilisation et les compositions pharmaceutiques contenant des nouveaux composés. Ces nouveaux composés sont utiles en thérapie, notamment pour le traitement du diabète sucré de type 2.
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