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Machine translation
1. (WO2002026734) PIPERAZIN-2-ONE AMIDES AS INHIBITORS OF FACTOR Xa
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026734    International Application No.:    PCT/US2001/030313
Publication Date: 04.04.2002 International Filing Date: 01.10.2001
IPC:
C07D 241/08 (2006.01), C07D 401/10 (2006.01), C07D 401/14 (2006.01), C07D 403/10 (2006.01), C07D 403/12 (2006.01), C07D 403/14 (2006.01), C07D 405/14 (2006.01), C07D 409/12 (2006.01), C07D 409/14 (2006.01), C07D 491/10 (2006.01)
Applicants: COR THERAPEUTICS, INC. [US/US]; 256 East Grand Avenue South San Francisco, CA 94080 (US) (For All Designated States Except US).
ZHU, Bing-Yan [CA/US]; (US) (For US Only).
SU, Ting [US/US]; (US) (For US Only).
LI, Wenhao [CN/US]; (US) (For US Only).
GOLDMAN, Erick, A. [US/US]; (US) (For US Only).
ZHANG, Penglie [CN/US]; (US) (For US Only).
JIA, Zhaozhong, Jon [CN/US]; (US) (For US Only).
SCARBOROUGH, Robert, M. [US/US]; (US) (For US Only)
Inventors: ZHU, Bing-Yan; (US).
SU, Ting; (US).
LI, Wenhao; (US).
GOLDMAN, Erick, A.; (US).
ZHANG, Penglie; (US).
JIA, Zhaozhong, Jon; (US).
SCARBOROUGH, Robert, M.; (US)
Agent: LEE, Christine, S.; Morgan, Lewis & Bockius LLP 1800 M. Street, NW Washington, DC 20036 (US)
Priority Data:
60/236,393 29.09.2000 US
Title (EN) PIPERAZIN-2-ONE AMIDES AS INHIBITORS OF FACTOR Xa
(FR) AMIDES PIPERAZINE-2-UN COMME INHIBITEURS DU FACTEUR XA
Abstract: front page image
(EN)Novel piperazin-2-one containing compounds of general formulae (I) or (II), including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivative having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and the compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
(FR)L"invention concerne de nouveaux composants contenant du pipérazine-2-un de formules générales (I) ou (II) : comprenant leur isomères, leurs sels, leurs hydrates, leurs solvats et leurs dérivés de promédicaments pharmaceutiquement acceptables possédant une activité contre le facteur Xa mammifère. L"invention concerne également les compositions contenant ces composants. Ces composants et ces compositions servent <i>in vitro</i> ou <i>in vivo</i> à empêcher ou traiter des conditions chez des mammifères caractérisées par une thrombose non-souhaitée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)