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Machine translation
1. (WO2002026712) QUATERNARY AMINES AND RELATED INHIBITORS OF FACTOR XA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026712    International Application No.:    PCT/US2001/042352
Publication Date: 04.04.2002 International Filing Date: 01.10.2001
Chapter 2 Demand Filed:    29.04.2002    
IPC:
C07D 213/74 (2006.01), C07D 213/81 (2006.01), C07D 409/12 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICALS, INC. [US/US]; 256 East Grand Avenue, South San Francisco, CA 94080 (US) (For All Designated States Except US).
ZHANG, Penglie [CN/US]; (US) (For US Only).
ZUCKETT, Jingmei, Fan [CN/US]; (US) (For US Only).
BAO, Liang [CN/US]; (US) (For US Only).
SCARBOROUGH, Robert, M. [US/US]; (US) (For US Only).
ZHU, Bing-Yan [CA/US]; (US) (For US Only)
Inventors: ZHANG, Penglie; (US).
ZUCKETT, Jingmei, Fan; (US).
BAO, Liang; (US).
SCARBOROUGH, Robert, M.; (US).
ZHU, Bing-Yan; (US)
Agent: LOWEN, Gregory, T.; Morgan, Lewis & Bockius LLP, 1111 Pennysylvania Avenue, NW, Washington, DC 20004 (US)
Priority Data:
60/236,330 29.09.2000 US
Title (EN) QUATERNARY AMINES AND RELATED INHIBITORS OF FACTOR XA
(FR) AMINES QUATERNAIRES ET INHIBITEURS DU FACTEUR XA ASSOCIES
Abstract: front page image
(EN)Novel quaternary amine-containing compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives,eg having the following structure: Wherein:A is having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
(FR)L'invention concerne de nouveaux composés contenant des amines quaternaires, leurs isomères pharmaceutiquement acceptables, sels, hydrates, solvates et des dérivés de prodrogue présentant une activité contre le facteur mammalien Xa. Cette invention concerne également des compositions contenant lesdits composés. Ces composés et compositions sont utiles in vitro ou in vivo pour prévenir ou traiter des états chez des mammifères caractérisés par une thrombose indésirée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)