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1. (WO2002026253) A VACCINE FOR ACIDS AND ITS PREPARATION AND USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026253    International Application No.:    PCT/CN2001/001190
Publication Date: 04.04.2002 International Filing Date: 20.07.2001
Chapter 2 Demand Filed:    20.07.2001    
IPC:
C07K 14/16 (2006.01)
Applicants: TSINGHUA UNIVERSITY [CN/CN]; Department of Biological Sciences & Biotechnology,, Tsinghuayuan, Haidian District, Beijing 100084 (CN) (For All Designated States Except US).
JIANGXI DRAGON-FIY SCIENCE AND TEHNOLOGY CO. LTD. [CN/CN]; No. 26 Ganfu Xilu, Taohua Sancun, Nanchang City, Kiangxi Provice 330009 (CN) (For All Designated States Except US).
BEIJING GUOXIWEIYE HIGH TECHNOLOGY DEVELOPMENT CO. LTD [CN/CN]; No. 61 Fuxing Road, Haidian District, Beijing 100036 (CN) (For All Designated States Except US).
CHEN, Yinghua [CN/CN]; (CN) (For US Only).
DING, Jian [CN/CN]; (CN) (For US Only).
LU, Yun [CN/CN]; (CN) (For US Only)
Inventors: CHEN, Yinghua; (CN).
DING, Jian; (CN).
LU, Yun; (CN)
Agent: JEEKAI & PARTNERS; Suite 602, Jinyu Tower, A129, West Street, Xuan Wu Men, Xicheng District, Beijing 100031 (CN)
Priority Data:
00 1 23487.0 18.08.2000 CN
Title (EN) A VACCINE FOR ACIDS AND ITS PREPARATION AND USE
(FR) VACCIN CONTRE LE SIDA, SON PROCEDE DE PREPARATION ET SES APPLICATIONS
Abstract: front page image
(EN)The invention discloses a vaccine for ACIDS, and its preparation and use, the present vaccine substantially comprises at least one epitope polypeptide, conjugated to carrier protein or carrier polypeptide to form conjugates, said epitope polypeptide comprises at least one epitope, derived from neutralizing epitope of human immunodeficiency virus (HIV) protein and its variations, or comprises at least two repeats of said epitope, or comprises CTL epitope and its variations. The method for preparing the present vaccine comprises: (1) synthesizing polypeptide; (2) conjugating said polypeptide to carrier protein or carrier polypeptide; (3) combining with adjuvant formulating the present vaccine.
(FR)L'invention concerne un vaccin contre le SIDA, son procédé de préparation et ses applications. Ledit vaccin renferme essentiellement au moins un polypeptide épitope conjugué à une protéine porteuse ou à un polypeptide porteur de manière à former des conjugués. Ledit polypeptide épitope contient un épitope de neutralisation de la protéine du virus de l'immunodéficience humaine et au moins un épitope provenant d'une de ses variantes ou un épitope de neutralisation de la protéine de l'immunodéficience humaine et au moins un épitope dupliqué une fois au minimum ou encore un épitope de la protéine de l'immunodéficience humaine et ses variantes. Le procédé de préparation du vaccin de cette invention consiste à 1) synthétiser de manière artificielle des polypeptides; 2) combiner ledit polypeptide au vecteur afin de former des conjugués distincts; 3) formuler un vaccin en combinant lesdits conjugués à l'aide d'un adjuvant. Ce vaccin peut servir de médicament à action préventive et thérapeutique contre le SIDA.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)