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Machine translation
1. (WO2002026224) METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026224    International Application No.:    PCT/US2001/030514
Publication Date: 04.04.2002 International Filing Date: 28.09.2001
Chapter 2 Demand Filed:    01.02.2002    
IPC:
A61K 31/05 (2006.01), A61K 31/352 (2006.01)
Applicants: IMMUGEN PHARMACEUTICALS, INC. [US/US]; 5901 Southwest 87th Street South Miami, FL 33143 (US) (For All Designated States Except US).
TRAVIS, Craig, R. [US/US]; (US) (For US Only)
Inventors: TRAVIS, Craig, R.; (US)
Agent: HEFNER, M., Daniel; Leydig, Voit & Mayer, Ltd. Two Prudential Plaza Suite 4900 180 North Stetson Chicago, IL 60601-6780 (US)
Priority Data:
60/236,408 28.09.2000 US
Title (EN) METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION
(FR) PROCEDES ET COMPOSES POUR INHIBER LE METABOLISME DES EICOSANOIDES ET L'AGREGATION PLAQUETTAIRE
Abstract: front page image
(EN)The invention provides a method for attenuating the aggregation and/or activation of blood platelets within a blood product. In accordance with the this method, a cannabinoid or resorcinolic compound is introduced into the blood product under conditions sufficient to inhibit the aggregation and/or activation of blood platelets within the blood product. The invention also pertains to he use of a cannabinoid or resorcinolic compound to prepare a composition suitable for inhibiting the activation and/or aggregation of blood platelets and to such compositions. The invention also pertains to a method of selectively inhibiting COX-1 and thromboxane synthase within a cell or blood platelet.
(FR)Cette invention se rapporte à un procédé servant à atténuer l'agrégation et/ou l'activation des plaquettes sanguines dans un produit sanguin. Selon ce procédé, on introduit un composé cannabinoïde ou résorcinolique dans le produit sanguin, dans des conditions propres à inhiber l'agrégation et/ou l'activation des plaquettes sanguines dans ce produit sanguin. Cette invention concerne également l'utilisation d'un composé cannabinoïde ou résorcinolique pour préparer une composition capable d'inhiber l'activation et/ou l'agrégation des plaquettes sanguines, et de telles compositions. Cette invention concerne en outre un procédé permettant d'inhiber sélectivement l'enzyme COX-1 et la thromboxane-synthase dans un globule ou une plaquette sanguine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)