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1. (WO2002026039) STABILISED COMPOSITIONS HAVING ANTIBACTERIAL ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/026039    International Application No.:    PCT/DK2001/000616
Publication Date: 04.04.2002 International Filing Date: 26.09.2001
Chapter 2 Demand Filed:    26.02.2002    
IPC:
A01N 43/50 (2006.01), A01N 43/54 (2006.01), A01N 59/16 (2006.01), A61L 26/00 (2006.01), C07D 233/74 (2006.01), C07D 233/80 (2006.01), C07D 233/88 (2006.01), C07D 239/62 (2006.01)
Applicants: COLOPLAST A/S [DK/DK]; Holtedam 1, DK-3050 Humlebaek (DK) (For All Designated States Except US).
VANGE, Jakob [DK/DK]; (DK) (For US Only).
NIELSEN, Brian [DK/DK]; (DK) (For US Only)
Inventors: VANGE, Jakob; (DK).
NIELSEN, Brian; (DK)
Agent: COLOPLAST A/S; Holtedam 1, DK-3050 Humblebæk, Att: Patent Department, Kim Nilausen (DK)
Priority Data:
PA 2000 01451 29.09.2000 DK
Title (EN) STABILISED COMPOSITIONS HAVING ANTIBACTERIAL ACTIVITY
(FR) COMPOSITIONS STABILISEES POSSEDANT UNE ACTIVITE ANTIBACTERIENNE
Abstract: front page image
(EN)A stabilised composition having antibacterial, antiviral and/or antifungal activity, said composition comprising silver ions and a ligand, characterised in that the composition comprises a complex of silver and a ligand selected from the group consisting of 5,5-disubstituted hydantoins in which the substituents do not comprise conjugated unsaturated bonds and barbituric acid and derivatives thereof stabilising silver ions against reduction to free silver in a hydrophilic environment, and that the composition has a solubility in water higher than 10 mg Ag/l is stable during sterilisation and retains the activity without giving rise to darkening or discoloration of the dressing during storage.
(FR)Composition stabilisée possédant une activité antibactérienne, antivirale et/ou antifongique et contenant des ions argent et un ligand. Cette composition contient, de façon caractéristique, un complexe d'argent et un ligand sélectionné dans le groupe constitué par des hydantoïnes 5,5-disubstituées dans lesquelles les substituants ne comprennent pas de liaisons conjuguées insaturées, ni d'acide barbiturique et ses dérivés, ce qui stabilise les ions argent contre leur réduction en argent libre dans un milieu hydrophile. Cette composition présente une solubilité dans l'eau supérieure à 10 mg Ag/l, conserve sa stabilité pendant la stérilisation et reste active sans produire de noircissement ni de décoloration du pansement pendant la conservation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)