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1. WO2002024943 - METHOD OF IDENTIFYING OSTEOREGENERATIVE AGENTS USING DIFFERENTIAL GENE EXPRESSION

Publication Number WO/2002/024943
Publication Date 28.03.2002
International Application No. PCT/US2001/029548
International Filing Date 19.09.2001
Chapter 2 Demand Filed 08.04.2002
IPC
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/51 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
51Bone morphogenic factor; Osteogenin; Osteogenic factor; Bone-inducing factor
C07K 14/635 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
635Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
G01N 33/74 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74involving hormones
CPC
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/51
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
C07K 14/635
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
635Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
C07K 2319/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
G01N 33/5008
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
Applicants
  • CURAGEN CORPORATION [US]/[US] (AllExceptUS)
  • GLAXO GROUP LIMITED [US]/[US] (AllExceptUS)
  • HORESOVSKY, Gregory, J. [US]/[US] (UsOnly)
  • NOEL, L., Stanton, III [US]/[US] (UsOnly)
  • RAHA, Debasiah [US]/[US] (UsOnly)
Inventors
  • HORESOVSKY, Gregory, J.
  • NOEL, L., Stanton, III
  • RAHA, Debasiah
Agents
  • ELRIFI, Ivor, R.
Priority Data
60/233,57919.09.2000US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF IDENTIFYING OSTEOREGENERATIVE AGENTS USING DIFFERENTIAL GENE EXPRESSION
(FR) METHODE D'IDENTIFICATION D'AGENTS OSTEOREGENERATEURS UTILISANT L'EXPRESSION DIFFERENTIELLE DE GENES
Abstract
(EN)
Disclosed are methods of identifying osteoregenerative agents using differential gene expression. Also disclosed are novel nucleic acid and polypeptide sequences whose expression is differentially regulated by parathyroid hormone.
(FR)
L'invention concerne des méthodes d'identification d'agents ostéorégénérateurs utilisant l'expression différentielle de gènes. L'invention concerne également de nouvelles séquences nucléotidiques et polypeptidiques dont l'expression est régulée de manière différentielle par l'hormone parathyroïde.
Also published as
Latest bibliographic data on file with the International Bureau