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1. WO2002024925 - 69109, A NOVEL HUMAN TYROSINE PHOSPHATASE AND USES THEREFOR

Publication Number WO/2002/024925
Publication Date 28.03.2002
International Application No. PCT/US2001/030118
International Filing Date 25.09.2001
Chapter 2 Demand Filed 04.04.2002
IPC
A61K 38/46 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
C12N 9/16 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
16acting on ester bonds (3.1)
C12Q 1/42 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
34involving hydrolase
42involving phosphatase
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 15/1137
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
1137against enzymes
C12N 2310/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2310Structure or type of the nucleic acid
10Type of nucleic acid
11Antisense
C12N 9/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
16acting on ester bonds (3.1)
C12Q 1/42
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
34involving hydrolase
42involving phosphatase
C12Y 301/03048
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
YENZYMES
301Hydrolases acting on ester bonds (3.1)
03Phosphoric monoester hydrolases (3.1.3)
03048Protein-tyrosine-phosphatase (3.1.3.48)
Applicants
  • MILLENNIUM PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • KAPELLER-LIBERMANN, Rosana [BR]/[US] (UsOnly)
Inventors
  • KAPELLER-LIBERMANN, Rosana
Agents
  • COLBY, Gary, D.
Priority Data
60/235,05325.09.2000US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) 69109, A NOVEL HUMAN TYROSINE PHOSPHATASE AND USES THEREFOR
(FR) NOUVELLE TYROSINE PHOSPHATASE HUMAINE APPELEE 69109 ET UTILISATIONS DE CETTE DERNIERE
Abstract
(EN)
The invention provides isolated nucleic acids molecules, designated 69109 nucleic acid molecules, which encode a novel human protein tyrosine phosphatase. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 69109 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a 69109 gene has been introduced or disrupted. The invention still further provides isolated 69109 proteins, fusion proteins, antigenic peptides and anti 69109 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
(FR)
La présente invention concerne des molécules d'acides nucléiques isolées, appelées molécules d'acides nucléiques 69109, qui codent une nouvelle tyrosine phosphatase protéique humaine; des molécules d'acides nucléiques antisens, des vecteurs d'expression de recombinaison contenant les molécules d'acides nucléiques 69109, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits et des animaux transgéniques non humains dans lesquels un gène 69109 a été introduit ou interrompu. Cette invention concerne également des protéines 69109 isolées, des protéines hybrides, des peptides antigéniques et des anticorps anti-69109; ainsi que des procédés de diagnostic dans lesquels on utilise les compositions selon l'invention.
Also published as
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