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1. WO2002022817 - NUCLEAR RECEPTOR L66 AND METHODS OF USE

Publication Number WO/2002/022817
Publication Date 21.03.2002
International Application No. PCT/EP2001/010323
International Filing Date 07.09.2001
Chapter 2 Demand Filed 23.11.2001
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/705 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/70567
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
70567Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
Applicants
  • LION BIOSCIENCE AG [DE]/[DE] (AllExceptUS)
  • CASARI, Georg [AT]/[DE] (UsOnly)
  • HÖFER, Michael [DE]/[DE] (UsOnly)
  • JACKSON, David [IE]/[DE] (UsOnly)
  • KRANZ, Harald [DE]/[DE] (UsOnly)
  • OTTE, Kerstin [DE]/[DE] (UsOnly)
  • REMMEL, Bettina [DE]/[DE] (UsOnly)
  • SUCKOW, Jörg [DE]/[DE] (UsOnly)
Inventors
  • CASARI, Georg
  • HÖFER, Michael
  • JACKSON, David
  • KRANZ, Harald
  • OTTE, Kerstin
  • REMMEL, Bettina
  • SUCKOW, Jörg
Agents
  • BOEHMERT & BOEHMERT Pettenkoferstrasse 20-22
Priority Data
00120370.216.09.2000EP
01111658.914.05.2001EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NUCLEAR RECEPTOR L66 AND METHODS OF USE
(FR) NOUVEAU RECEPTEUR NUCLEAIRE DE MAMMIFERE L66 ET SES METHODES D'UTILISATION
Abstract
(EN)
The present invention relates to a novel nuclear receptor called 'L66' or also FXR-$g(b) a homologue of the FXR-$g(a), a prototypical type 2 nuclear receptor. The invention also relates to the isolated nucleic acid sequence of L66 and the isolated protein thereof. The invention further relates to processes for isolating and/or producing the nucleic acid or the protein as well as methods of use of the receptor L66.
(FR)
La présente invention concerne un nouveau récepteur nucléaire appelé « L66 » ou également FXR-$g(b), un homologue de FXR-$g(a), un prototype de récepteur nucléaire de type 2. L'invention concerne également la séquence d'acide nucléique isolée de L66 et la protéine isolée liée à la séquence d'acide nucléique isolée. L'invention concerne également des procédés permettant d'isoler et/ou de produire cet acide nucléique ou cette protéine, ainsi que des méthodes d'utilisation de ce récepteur L66.
Also published as
Latest bibliographic data on file with the International Bureau