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1. WO2002022773 - BIOREACTOR

Publication Number WO/2002/022773
Publication Date 21.03.2002
International Application No. PCT/EP2001/010668
International Filing Date 14.09.2001
Chapter 2 Demand Filed 05.04.2002
IPC
C12M 1/12 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
12with sterilisation, filtration, or dialysis means
CPC
C12M 29/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
29Means for introduction, extraction or recirculation of materials, e.g. pumps
04Filters; Permeable or porous membranes or plates, e.g. dialysis
Applicants
  • SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. [NL]/[NL] (AllExceptUS)
  • CORCHO-SANCHEZ, Diego [ES]/[GB] (UsOnly)
  • LERNER, David, Nicholas [GB]/[GB] (UsOnly)
  • STEPHENSON, Richard, John [GB]/[GB] (UsOnly)
  • WATKINSON, Robert, James [GB]/[GB] (UsOnly)
Inventors
  • CORCHO-SANCHEZ, Diego
  • LERNER, David, Nicholas
  • STEPHENSON, Richard, John
  • WATKINSON, Robert, James
Priority Data
00308047.015.09.2000EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIOREACTOR
(FR) BIOREACTEUR
Abstract
(EN)
A bioreactor for microbial conversion of at least one conversion substrate, which comprises a treatment zone to accommodate when in use a solution of said at least one conversion substrate, a culture holding zone to accommodate when in use a microbial culture capable of metabolising said at least one conversion substrate, a source of primary growth substrate for the microbial culture, a first permeable membrane forming an interface between the treatment zone and the culture holding zone, and a second permeable membrane forming an interface between the source of primary growth substrate and the culture holding zone, the first permeable membrane being of a material which will allow passage of the at least one conversion substrate from the treatment zone to the culture holding zone whilst being impermeable to the microbial culture, the second permeable membrane being of a material permeable to the primary growth substrate but substantially impermeable to water; and a process of operating said bioreactor.
(FR)
L'invention concerne un bioréacteur pour la conversion microbienne d'au moins un substrat de conversion, qui comprend une zone de traitement recevant, à l'utilisation, une solution du ou des substrats de conversion, une zone de maintien de culture recevant, à l'utilisation, une culture microbienne capable de métaboliser le ou les substrats de conversion, une source de substrat de croissance primaire pour la culture microbienne, une première membrane perméable formant une interface entre la zone de traitement et la zone de maintien de culture, et une seconde membrane perméable formant une interface entre la source de substrat de croissance primaire et la zone de maintien de culture, sachant que la première membrane perméable est en matériau qui laisse passer le ou les substrats de conversion depuis la zone de traitement vers la zone de maintien de culture et qui est imperméable à la culture microbienne, et sachant par ailleurs que la seconde membrane perméable est en matériau perméable au substrat de croissance primaire mais sensiblement imperméable à l'eau. L'invention concerne un procédé relatif au fonctionnement de ce bioréacteur.
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