Processing

Please wait...

Settings

Settings

Goto Application

1. WO2002020486 - PICOLINIC ACID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF CANCER IN ANIMALS

Publication Number WO/2002/020486
Publication Date 14.03.2002
International Application No. PCT/US2001/027578
International Filing Date 05.09.2001
Chapter 2 Demand Filed 04.04.2002
IPC
A61K 31/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
C07D 213/79 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
02having three double bonds between ring members or between ring members and non-ring members
04having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
60with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
79Acids; Esters
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/07
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
07Retinol compounds, e.g. vitamin A
A61K 31/429
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
425Thiazoles
429condensed with heterocyclic ring systems
A61K 31/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
A61K 31/4402
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4402only substituted in position 2, e.g. pheniramine, bisacodyl
A61K 31/4965
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
4965Non-condensed pyrazines
Applicants
  • NOVACTYL, INC. [US]/[US]
Inventors
  • FERNANDEZ-POL, Jose, A.
Agents
  • AMOS, Ahaji, K.
Priority Data
09/657,55408.09.2000US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PICOLINIC ACID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF CANCER IN ANIMALS
(FR) AGENT ET PROCEDE SERVANT A PREVENIR ET A TRAITER LE CANCER CHEZ L'ANIMAL
Abstract
(EN)
An antiproliferative, anti inflammatory, antiinfective, immunization agent of a metalion chelating agent such as picolinic acid or derivatives thereof, and methods of using thesame. The agents chelate metals in metal containing protein complexes and enzymes required for growth, replication or inflammatory response. The preparations can be administered systemically or for topical use. The preparations have antineoplastic, antiviral, antiinflammatory, analgesic antiangiogenic and antiproliferative effects and are used in the treatment of warts, psoriasis, acne, skin cancers, sunburn, inflammatory responses, untoward anglogenesis and other diseases and in the prevention of sexually transmitted diseases such as genital warts, herpes and AIDS.
(FR)
Agent antiprolifératif, anti-inflammatoire, anti-infectieux, immunisant consistant en un agent séquestrant d'ions métaux tels qu'acide picolinique ou ses dérivés, ainsi que procédés servant à utiliser cet agent. Ces agents séquestrent des métaux dans des complexes de protéine contenant des métaux et dans des enzymes nécessaires à la croissance, à la réplication ou à la réaction inflammatoire. On peut administre ces préparations de façon systémique ou topique. Ces préparations exercent des effets antinéoplasiques, antiviraux, anti-inflammatoires, analgésiques, anti-angiogéniques et anti-prolifératifs et on les utilise afin de traiter des verrues, le psoriasis, l'acné, les cancers de la peau, les coups de soleil, les réactions inflammatoires, l'angiogénèse indirecte et d'autres maladies, et pour la prévention de maladies sexuellement transmissibles, telles que les lésions génitales, l'herpès et le SIDA.
Also published as
Latest bibliographic data on file with the International Bureau