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1. WO2002018447 - FUSION PROTEIN CONTAINING ADDITIONAL CATIONIC AMINO ACIDS AND IMPROVEMENT OF BIO-OPERATION BY USING SAME

Publication Number WO/2002/018447
Publication Date 07.03.2002
International Application No. PCT/KR2001/001394
International Filing Date 17.08.2001
Chapter 2 Demand Filed 22.02.2002
IPC
C07K 1/113 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
107by chemical modification of precursor peptides
113without change of the primary structure
C07K 19/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
C12N 9/10 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10Transferases (2.)
CPC
C07K 1/1136
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
107by chemical modification of precursor peptides
113without change of the primary structure
1136by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
C12N 9/1074
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
10Transferases (2.)
1048Glycosyltransferases (2.4)
1051Hexosyltransferases (2.4.1)
1074Cyclomaltodextrin glucanotransferase (2.4.1.19)
Applicants
  • BIONGENE CO., LTD. [KR]/[KR] (AllExceptUS)
  • SHIN, Chul, Soo [KR]/[KR] (AllExceptUS)
  • SEO, Jin, Ho [KR]/[KR]
  • KWEON, Dae, Hyuk [KR]/[KR] (UsOnly)
  • HAN, Nam, Soo [KR]/[KR] (UsOnly)
  • RHA, Chan, Su [KR]/[KR] (UsOnly)
Inventors
  • SEO, Jin, Ho
  • KWEON, Dae, Hyuk
  • HAN, Nam, Soo
  • RHA, Chan, Su
Agents
  • JANG, Seong Ku
Priority Data
2000/4776818.08.2000KR
Publication Language English (EN)
Filing Language Korean (KO)
Designated States
Title
(EN) FUSION PROTEIN CONTAINING ADDITIONAL CATIONIC AMINO ACIDS AND IMPROVEMENT OF BIO-OPERATION BY USING SAME
(FR) PROTEINE DE FUSION CONTENANT DES ACIDES AMINES CATIONIQUES SUPPLEMENTAIRES ET AMELIORATION D'UNE BIO-OPERATION GRACE A L'UTILISATION DE LADITE PROTEINE
Abstract
(EN)
A fusion protein having more than two consecutive cationic amino acid residues selected from the group consisting of lysine and arginine in addition to a desired protein is provided, by which the purification, immobilization and refolding efficiencies of the desired protein are enhanced.
(FR)
L'invention concerne une protéine de fusion contenant plus de deux restes d'acides aminés cationiques consécutifs sélectionnés dans le groupe comprenant la lysine et l'arginine et ajoutée à une protéine désirée, permettant d'améliorer l'efficacité de purification, d'immobilisation et de renaturation de la protéine désirée.
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