Processing

Please wait...

Settings

Settings

Goto Application

1. WO2002017915 - BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS

Publication Number WO/2002/017915
Publication Date 07.03.2002
International Application No. PCT/GB2001/003862
International Filing Date 30.08.2001
Chapter 2 Demand Filed 11.03.2002
IPC
C07D 277/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
277Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
02not condensed with other rings
20having two or three double bonds between ring members or between ring members and non-ring members
C07D 417/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
CPC
A61P 31/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
10Antimycotics
C07D 277/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
277Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
02not condensed with other rings
20having two or three double bonds between ring members or between ring members and non-ring members
C07D 417/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • OXFORD GLYCOSCIENCES (UK) LIMITED [GB]/[GB] (AllExceptUS)
  • ORCHARD, Michael, Glen [GB]/[GB] (UsOnly)
  • NEUSS, Judi, Charlotte [GB]/[GB] (UsOnly)
  • GALLEY, Carl, Maurice, Swedler [GB]/[GB] (UsOnly)
Inventors
  • ORCHARD, Michael, Glen
  • NEUSS, Judi, Charlotte
  • GALLEY, Carl, Maurice, Swedler
Agents
  • CHAPMAN, Paul, William
Priority Data
0021421.331.08.2000GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS
(FR) THIAZOLIDINEDIONES DE BENZYLIDENE ET LEUR UTILISATION EN TANT QU'AGENTS ANTIFONGIQUES
Abstract
(EN)
A compound of formula I or a salt thereof wherein, A is O or S, X and Y independently represent O, CH2 and may be the same or different, Q is (CH2)m-CH(R1)-(CH2)n, R is OR6, NHR8, R1 is hydrogen, or optionally substituted alkyl, R2 and R3 are independently hydrogen, or specific substituents, provided that R2 and R3 are not both H, and R4 and R5 are hydrogen or specific substituents, m is 0-3; n is 0-2; are useful in the treatment of fungal infections.
(FR)
La présente invention concerne un composé de formule (I) ou un sel de celui-ci. Dans cette formule, A représente O ou S, X et Y représentent indépendamment O ou CH2 et peuvent être identiques ou différents, Q représente (CH2)m-CH(R1)-(CH2)n, R représente OR6, NHR8, R1 représente hydrogène ou alkyle éventuellement substitué, R2 et R3 représentent indépendamment hydrogène ou des substituants spécifiques, sous réserve que R2 et R3 ne soient pas tous les deux H, R4 et R5 représentent hydrogène ou des substituants spécifiques, m vaut de 0 à 3 et n vaut de 0 à 2. Les composés selon cette invention sont utilisés dans le traitement d'infections fongiques.
Latest bibliographic data on file with the International Bureau