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1. (WO2002008395) PUTATIVE HUMAN METHYLTRANSFERASE FAMILY MEMBER AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/008395    International Application No.:    PCT/US2001/022321
Publication Date: 31.01.2002 International Filing Date: 16.07.2001
Chapter 2 Demand Filed:    28.01.2002    
IPC:
C12N 9/10 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICALS, INC. [US/US]; 75 Sidney Street Cambridge, MA 02139 (US) (For All Designated States Except US).
MEYERS, Rachel, E. [US/US]; (US) (For US Only).
TSAI, Fong-Ying [--/US]; (US) (For US Only)
Inventors: MEYERS, Rachel, E.; (US).
TSAI, Fong-Ying; (US)
Agent: MANDRAGOURAS, Amy, E.; Lahive & Cockfield, LLP 28 State Street Boston, MA 02109 (US)
Priority Data:
60/218,470 14.07.2000 US
Title (EN) PUTATIVE HUMAN METHYLTRANSFERASE FAMILY MEMBER AND USES THEREOF
(FR) 42755, UNE NOUVEAU MEMBRE DE LA FAMILLE DE LA METHYL-TRANSFERASE HUMAINE ET SES APPLICATIONS
Abstract: front page image
(EN)The invention provides isolated nucleic acid molecules, designated METH-1 nucleic acid molecules, which encode novel methyltransferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing METH-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a METH-1 gene has been introduced or disrupted. The invention still furhter provides isolated METH-1 proteins, fusion proteins, antigenic peptides and anti-METH-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
(FR)La présente invention concerne des molécules isolées d'acide nucléique, appelées molécules d'acide nucléique METH-1, codant pour de nouveaux membres de la famille de la méthyl-transférase. L'invention concerne également des molécules antisens d'acide nucléique, des vecteurs d'expression recombinants contenant des molécules d'acide nucléique METH-1, des cellules hôtes dans lesquelles ont été introduits les vecteurs d'expression, et des animaux transgéniques non humains dans lesquels un gène METH-1 a été introduit ou perturbé. L'invention concerne en outre des protéines METH-1 isolées, des protéines hybrides, des peptides antigéniques et des anticorps anti-METH-1. Enfin, l'invention concerne des méthodes de diagnostic mettant en oeuvre des compositions selon l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)