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1. WO2002008352 - MEDICAL CONTACT ADHESIVE COMPRISING A TWO PHASE ADHESIVE MATRIX OF POLYACRYLATES AND POLYAMINE SALTS

Publication Number WO/2002/008352
Publication Date 31.01.2002
International Application No. PCT/EP2001/007982
International Filing Date 11.07.2001
Chapter 2 Demand Filed 26.01.2002
IPC
A61K 9/70 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
A61L 15/58 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42Use of materials characterised by their function or physical properties
58Adhesives
C08L 33/06 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
33Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Compositions of derivatives of such polymers
04Homopolymers or copolymers of esters
06of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
C09J 133/14 2006.1
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
JADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
133Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
04Homopolymers or copolymers of esters
14of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
CPC
A61K 9/7061
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
7053obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
7061Polyacrylates
A61L 15/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42Use of materials characterised by their function or physical properties
58Adhesives
A61P 25/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
04Centrally acting analgesics, e.g. opioids
C08L 2205/18
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2205Polymer mixtures characterised by other features
14containing polymeric additives characterised by shape
18Spheres
C08L 2666/04
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2666Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
02Organic macromolecular compounds, natural resins, waxes or and bituminous materials
04Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof
C08L 33/064
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
33Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
04Homopolymers or copolymers of esters
06of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
062Copolymers with monomers not covered by C08L33/06
064containing anhydride, COOH or COOM groups, with M being metal or onium-cation
Applicants
  • LTS LOHMANN THERAPIE-SYSTEM AG [DE]/[DE] (AllExceptUS)
  • KOCH, Andreas [DE]/[DE] (UsOnly)
  • BRACHT, Stefan [DE]/[DE] (UsOnly)
  • SCHMITZ, Christoph [DE]/[DE] (UsOnly)
Inventors
  • KOCH, Andreas
  • BRACHT, Stefan
  • SCHMITZ, Christoph
Agents
  • FLACCUS, Rolf-Dieter
Priority Data
100 35 891.824.07.2000DE
Publication Language German (de)
Filing Language German (DE)
Designated States
Title
(DE) MEDIZINISCHER HAFTKLEBER MIT EINER ZWEIPHASIGEN KLEBERMATRIX AUS POLYACRYLATEN UND POLYAMINSALZEN
(EN) MEDICAL CONTACT ADHESIVE COMPRISING A TWO PHASE ADHESIVE MATRIX OF POLYACRYLATES AND POLYAMINE SALTS
(FR) ADHESIF MEDICAL A MATRICE ADHESIVE A DEUX PHASES A BASE DE POLYACRYLATES ET DE SELS DE POLYAMINE
Abstract
(DE) Ein medizinischer Haftkleber auf der Basis von Polyacrylaten und neutralen Polyaminsalzen ist dadurch gekennzeichnet, daß er eine Haftmatrix aus zwei Polymerkomponenten A und B aufweist, wobei Polymerkomponente A ein carboxylgruppenhaltiger Polyacrylathaftkleber ist, dessen Carboxylgruppen neutralisiert sind; Polymerkomponente B ein neutrales Polyaminsalz ist, welches durch Umsetzung eines aminogruppenhaltigen Polyacrylat-Copolymers mit einer Säure erhalten wurde, und wobei die Polymerkomponente B in der Polymerkomponente A dispergiert ist und die beiden Komponenten ein zweiphasiges System bilden.
(EN) The invention relates to a medical adhesive based on polyacrylates and neutral polyamine salts, characterised in that it comprises an adhesive matrix of two polymer components A and B. Polymer component A is a polyacrylate adhesive containing carboxyl groups which are neutralised. Polymer component B is a neutral polyamine salt, obtained by reacting of a polyacrylate copolymer containing amino groups with an acid. Polymer component B is dispersed in polymer component A and both components form a two phase system.
(FR) L'invention concerne un adhésif médical à base de polyacrylates et de sels neutres de polyamine. L'invention est caractérisée en ce que ledit adhésif comporte une matrice adhésive constituée de deux composants polymères A et B. Le composant polymère A est un adhésif polyacrylate contenant des groupes carboxyles neutralisés. Le composant polymère B est un sel de polyamine neutre obtenu par la réaction d'un copolymère de polyacrylate contenant des groupes amino avec un acide. Le composant polymère B est dispersé dans le composant polymère A, ces deux composants constituant un système à deux phases.
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