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1. (WO2002006337) A NOVEL POLYPEPTIDE - HUMAN HYDROXYINDOLE-O-METHYL-TRANSFERASE 12.43 AND A POLYNUCLEOTIDE ENCODING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/006337    International Application No.:    PCT/CN2001/001111
Publication Date: 24.01.2002 International Filing Date: 29.06.2001
IPC:
A61K 38/00 (2006.01), C12N 9/10 (2006.01)
Applicants: SHANGHAI BIOWINDOW GENE DEVELOPMENT INC. [CN/CN]; 12th Floor, 3rd Building No. 1111, Zhongshan Bei Er Road Shanghai 200092 (CN) (For All Designated States Except US).
MAO, Yumin [CN/CN]; (CN) (For US Only).
XIE, Yi [CN/CN]; (CN) (For US Only)
Inventors: MAO, Yumin; (CN).
XIE, Yi; (CN)
Agent: SHANGHAI HUA DONG PATENT AGENCY; 319 Yue Yang Road Shanghai 200031 (CN)
Priority Data:
00116947.5 30.06.2000 CN
Title (EN) A NOVEL POLYPEPTIDE - HUMAN HYDROXYINDOLE-O-METHYL-TRANSFERASE 12.43 AND A POLYNUCLEOTIDE ENCODING THE SAME
(FR) NOUVEAU POLYPEPTIDE, HYDROXYINDOLE-O-METHYL TRANSFERASE HUMAINE 12.43, ET POLYNUCLEOTIDE CODANT CE POLYPEPTIDE
Abstract: front page image
(EN)The present invention discloses a novel polypeptide human hydroxyindole-O-methyltransferase 12.43 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technique. The present invention also discloses methods of using the polypeptide in treatment of various disease, such as disease associated with disturbance of immunological function, tumor, Alzheimer disease, insomnia and so on. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding human hydorxyindole-O-methyltransferase 12.43.
(FR)L'invention concerne un nouveau polypeptide, une hydroxyindole-O-méthyl transférase humaine 12.43, et un polynucléotide codant ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment de dysfonctionnements immunitaires, de tumeurs, de la maladie d'Alzheimer et d'insomnies. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant l'hydroxyindole-O-méthyl transférase humaine 12.43.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)