WO2002005841 TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

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Publication Number WO/2002/005841

Publication Date 24.01.2002

International Application No. PCT/US2001/021651

International Filing Date 10.07.2001

Chapter 2 Demand Filed 25.01.2002

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Applicants

DUKE UNIVERSITY [US]/[US] (AllExceptUS)
CHEN, Yuan-Tsong [US]/[US] (UsOnly)

Inventors

CHEN, Yuan-Tsong

Agents

BROOK, David, E.

Priority Data

60/219,237

18.07.2000

Publication Language English (en)

Filing Language English (EN)

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Title

(EN) TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

(FR) TRAITEMENT DE LA GLYCOGENOSE DE TYPE II

Abstract

(EN) Methods of treating glycogen storage disease type II, by administering acid $g(a)-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.

(FR) L'invention concerne des méthodes permettant de traiter la glycogénose de type II, par administration d'$g(a)-glucosidase acide. L'invention concerne également des compositions pouvant être utilisées pour le traitement de la glycogénose de type II.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
04	Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12	Cyclic peptides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43	Enzymes; Proenzymes; Derivatives thereof
46	Hydrolases (3)
47	acting on glycosyl compounds (3.2), e.g. cellulases, lactases

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
04	Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12	Cyclic peptides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43	Enzymes; Proenzymes; Derivatives thereof
46	Hydrolases (3)
47	acting on glycosyl compounds (3.2), e.g. cellulases, lactases

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides

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1. WO2002005841 - TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21	Drugs for disorders of the muscular or neuromuscular system

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Y	ENZYMES
302	Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
01	Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
0102	Alpha-glucosidase (3.2.1.20)