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Machine translation
1. (WO2002005815) OPHTHALMIC FORMULATION OF A SELECTIVE CYCLOOXYGENASE-2 INHIBITORY DRUG
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/005815    International Application No.:    PCT/US2001/022061
Publication Date: 24.01.2002 International Filing Date: 12.07.2001
Chapter 2 Demand Filed:    13.02.2002    
IPC:
A61K 9/00 (2006.01), A61K 9/14 (2006.01), A61K 9/51 (2006.01), A61K 31/12 (2006.01), A61K 31/122 (2006.01), A61K 31/352 (2006.01), A61K 31/353 (2006.01), A61K 31/365 (2006.01), A61K 31/38 (2006.01), A61K 31/415 (2006.01), A61K 31/42 (2006.01), A61K 31/435 (2006.01), A61K 31/44 (2006.01), A61K 31/4418 (2006.01), A61K 31/444 (2006.01), A61K 31/465 (2006.01), A61K 31/47 (2006.01), A61K 31/50 (2006.01), A61K 31/635 (2006.01), A61K 31/74 (2006.01), A61K 45/06 (2006.01), A61K 47/10 (2006.01), A61K 47/14 (2006.01), A61K 47/26 (2006.01), A61K 47/32 (2006.01), A61K 47/38 (2006.01)
Applicants: PHARMACIA & UPJOHN COMPANY [US/US]; 301 Henrietta Street, Kalamazoo, MI 49001 (US) (For All Designated States Except US).
KARARLI, Tugrul, T. [US/US]; (US) (For US Only).
BANDYOPADHYAY, Rebanta [IN/US]; (US) (For US Only).
SINGH, Satish, K. [SE/US]; (US) (For US Only).
HAWLEY, Leslie, C. [US/US]; (US) (For US Only)
Inventors: KARARLI, Tugrul, T.; (US).
BANDYOPADHYAY, Rebanta; (US).
SINGH, Satish, K.; (US).
HAWLEY, Leslie, C.; (US)
Agent: CHAPMAN, Terryence, F.; Flynn, Thiel, Boutell & Tanis, P.C., 2026 Rambling Road, Kalamazoo, MI 49008-1699 (US)
Priority Data:
60/218,101 13.07.2000 US
60/279,285 28.03.2001 US
60/294,838 31.05.2001 US
60/296,388 06.06.2001 US
Title (EN) OPHTHALMIC FORMULATION OF A SELECTIVE CYCLOOXYGENASE-2 INHIBITORY DRUG
(FR) PREPARATION OPHTALMIQUE D'UN MEDICAMENT INHIBITEUR SELECTIF DE CYCLOOXYGENASE-2.
Abstract: front page image
(EN)There is provided a pharmaceutical composition suitable for topical administration to an eye which contains a selective COX-2 inhibitory drug or nanoparticles of a drug of low water solubility, in a concentration effective for treatment and/or prophylaxis of a disorder in the eye, and one or more ophthalmically acceptable excipients that reduce rate of removal from the eye such that the composition has an effective residence time of about 2 to about 24 hours. Also provided is a method of treating and/or preventing a disorder in an eye, the method comprising administering to the eye a composition of the invention.
(FR)L'invention concerne une composition pharmaceutique conçue pour une administration topique à un oeil, laquelle renferme un médicament inhibiteur sélectif de COX-2 ou des nanoparticules d'un médicament à faible hydrosolubilité, dans une concentration efficace pour le traitement et/ou la prophylaxie d'un trouble oculaire, ainsi qu'un ou plusieurs véhicules acceptables sur le plan ophtalmique permettant de réduire la vitesse de retrait de la composition de l'oeil, de manière que celle-ci présente un temps de résidence efficace compris entre environ 2 et environ 24 heures. L'invention concerne en outre un procédé de traitement et/ou de prévention d'un trouble oculaire, le procédé consistant à administrer une composition selon l'invention à un oeil.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)