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1. (WO2002005786) PHARMACEUTICAL COMPOSITION IMPROVED IN PERORAL ABSORBABILITY

Pub. No.:    WO/2002/005786    International Application No.:    PCT/JP2001/006135
Publication Date: Jan 24, 2002 International Filing Date: Jul 16, 2001
IPC: A61K 31/663
A61K 47/12
A61K 47/32
Applicants: YAMANOUCHI PHARMACEUTICAL CO., LTD.

WATANABE, Shunsuke

TAKEMURA, Shigeo

TSUTSUI, Yuuki

KONDO, Hiromu

NAKANISHI, Kiyo

SAKO, Kazuhiro

SAWADA, Toyohiro

Inventors: WATANABE, Shunsuke

TAKEMURA, Shigeo

TSUTSUI, Yuuki

KONDO, Hiromu

NAKANISHI, Kiyo

SAKO, Kazuhiro

SAWADA, Toyohiro

Title: PHARMACEUTICAL COMPOSITION IMPROVED IN PERORAL ABSORBABILITY
Abstract:
A pharmaceutical composition improved in peroral absorbability, which comprises a drug, aminoalkyl methacrylate copolymer E, and an acid substance and in which the three components stand adjacent to each another and at least the copolymer and the acid substance are uniformly dispersed; a method for improving peroral absorbability by using the composition; and a peroral absorption improver for enhancing the penetration of drug into the gastrointestinal mucosa and/or the mucous blanket present on the surface thereof, which contains aminoalkyl methacrylate copolymer E as the active ingredient.