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Machine translation
1. (WO2002004601) MAMMALIAN MDM2 BINDING PROTEINS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/004601    International Application No.:    PCT/US2001/022053
Publication Date: 17.01.2002 International Filing Date: 12.07.2001
Chapter 2 Demand Filed:    06.02.2002    
IPC:
C07K 14/47 (2006.01)
Applicants: PHILADELPHIA, HEALTH AND EDUCATION CORPORATION [US/US]; Broad and Vine Streets Philadelphia, PA 19102 (US) (For All Designated States Except US).
BOYD, Mark, Thomas [GB/GB]; (GB) (For US Only).
HAINES, Dale, Stewart [US/US]; (US) (For US Only).
VLATKOVIC, Nikolina [--/GB]; (GB) (For US Only)
Inventors: BOYD, Mark, Thomas; (GB).
HAINES, Dale, Stewart; (US).
VLATKOVIC, Nikolina; (GB)
Agent: LICATA, Jane, Massey; Licata & Tyrrell P.C. 66 E. Main Street Marlton, NJ 08053 (US)
Priority Data:
60/217,835 12.07.2000 US
60/230,894 05.09.2000 US
Title (EN) MAMMALIAN MDM2 BINDING PROTEINS AND USES THEREOF
(FR) PROTEINES MAMMIFERES SE LIANT A MDM2 ET LEURS APPLICATIONS
Abstract: front page image
(EN)Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G¿1? phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.
(FR)L'invention concerne des séquences d'acide nucléique isolées qui codent pour une protéine mammifère se liant à MDM2, et des séquences polypeptidiques de la protéine mammifère se liant à MDM2. L'invention concerne aussi des vecteurs contenant ces séquences d'acide nucléique, des cellules hôtes qui expriment ces protéines et des anticorps dirigés contre ces protéines. De plus, l'invention concerne des procédés et des compositions servant à moduler la phase G¿1? du cycle cellulaire par une modification de l'expression et/ou de l'activité d'une protéine mammifère se liant à MDM2.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)