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1. (WO2002004429) PYRIMIDINE DERIVATIVES

Pub. No.:    WO/2002/004429    International Application No.:    PCT/GB2001/003084
Publication Date: Jan 17, 2002 International Filing Date: Jul 6, 2001
IPC: A61K 31/505
C07D 239/48
C07D 401/12
C07D 403/04
C07D 403/12
Applicants: ASTRAZENECA AB
ASTRAZENECA UK LIMITED
THOMAS, Andrew, Peter
NEWCOMBE, Nicholas, John
HEATON, David, William
Inventors: THOMAS, Andrew, Peter
NEWCOMBE, Nicholas, John
HEATON, David, William
Title: PYRIMIDINE DERIVATIVES
Abstract:
Compounds of formula (I), wherein R?1, p, R2, q, R3 and R4¿ are defined within, and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.