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1. (WO2002004419) $g(a),$g(a)-DIBROMO-$g(a)-CHLORO-ACETOPHENONES AS SYNTHONS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2002/004419 International Application No.: PCT/US2001/021623
Publication Date: 17.01.2002 International Filing Date: 10.07.2001
Chapter 2 Demand Filed: 01.02.2002
C07C 45/46 (2006.01) ,C07C 45/63 (2006.01) ,C07C 49/80 (2006.01) ,C07C 49/813 (2006.01) ,C07C 49/84 (2006.01) ,C07C 67/00 (2006.01) ,C07C 67/343 (2006.01) ,C07C 231/10 (2006.01) ,C07C 235/60 (2006.01) ,C07D 211/26 (2006.01) ,C07D 213/74 (2006.01) ,C07D 295/182 (2006.01)
Applicants: RAY, Anup, Kumar[IN/US]; US (UsOnly)
PATEL, Hiren, Kumar, V.[IN/US]; US (UsOnly)
MERAI, Shilpa, V.[IN/US]; US (UsOnly)
PATEL, Mahendra, R.[US/US]; US (UsOnly)
GENEVA PHARMACEUTICALS, INC.[US/US]; 2655 West Midway Boulevard Broomfield, CO 80038, US (AllExceptUS)
Inventors: RAY, Anup, Kumar; US
PATEL, Hiren, Kumar, V.; US
MERAI, Shilpa, V.; US
PATEL, Mahendra, R.; US
Agent: FURMAN, Diane, E. ; Novartis Pharmaceuticals Corporation Patent & Trademark Department 564 Morris Avenue Summit, NJ 07901-1027, US
Priority Data:
Abstract: front page image
(EN) This disclosure relates to the use of $g(a),$g(a)-dibromo-$g(a)-chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-$g(a),$g(a)-dibromo-$g(a)-chloro-acetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical.
(FR) La présente invention concerne l'utilisation de composés de $g(a),$g(a)-dibromo-$g(a)-chloroacétophénone en tant qu'intermédiaires pour préparer des composés carbonyle aromatique, et plus spécifiquement des amides aromatiques. Le composé 2,5-bis(2,2,2-trifluoroéthoxy)-$g(a),$g(a)-dibromo-$g(a)-chloro-acétophénone est tout particulièrement utile en tant qu'intermédiaire pour préparer le flécaïnide, lequel est une substance pharmaceutique connue.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)