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1. (WO2002003965) METHOD FOR FORMULATING HEALTHCARE PRODUCTS WITH ENHANCED STABILITY

Pub. No.:    WO/2002/003965    International Application No.:    PCT/US2001/021418
Publication Date: Jan 17, 2002 International Filing Date: Jul 6, 2001
IPC: A61K 9/20
A61K 9/28
Applicants: DELSYS PHARMACEUTICAL CORPORATION
MURARI, Ramaswamy
KATDARE, Ashok
CHRAI, Suggy, S.
HARMON, Troy, M.
Inventors: MURARI, Ramaswamy
KATDARE, Ashok
CHRAI, Suggy, S.
HARMON, Troy, M.
Title: METHOD FOR FORMULATING HEALTHCARE PRODUCTS WITH ENHANCED STABILITY
Abstract:
A method is disclosed for formulating healthcare products, including solid pharmaceutical compositions, while avoiding instability caused ba interaction of the active ingredient with excipients. The method comprises the steps of: (a) selecting an active ingredient that loses stability or potency upon interaction with pharmaceutical excipients; and (b) depositing the active ingredient, preferably electrostatically, as a dry powder substantially free of excipients, onto a pharmaceutically acceptable polymer substrate.