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1. (WO2002003063) USE OF DISEASE-ASSOCIATED GENE

Pub. No.:    WO/2002/003063    International Application No.:    PCT/JP2001/005652
Publication Date: Jan 10, 2002 International Filing Date: Jun 29, 2001
IPC: A61K 38/00
C07K 14/47
G01N 33/68
Applicants: TAKEDA CHEMICAL INDUSTRIES, INC.

KOYAMA, Nobuyuki

TANIDA, Seiichi

WATANABE, Toshifumi

Inventors: KOYAMA, Nobuyuki

TANIDA, Seiichi

WATANABE, Toshifumi

Title: USE OF DISEASE-ASSOCIATED GENE
Abstract:
A method of screening a drug by using a disease-associated gene product; an antibody against the disease-associated gene product; an antisense DNA inhibiting the expression of the disease-associated gene, etc. A compound regulating the activity of a protein having an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1 or its salt, a neutralizing antibody regulating the activity of the above protein, an antisense DNA, etc. can regulate the expression of the protein having an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1 and, therefore, are usable as preventives and remedies for diseases such as heart diseases.