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1. WO2002002613 - A NOVEL POLYPEPTIDE - HUMAN OXYSTEROL-BINDING PROTEIN 38.72 AND A POLYNUCLEOTIDE ENCODING THE SAME

Publication Number WO/2002/002613
Publication Date 10.01.2002
International Application No. PCT/CN2001/000955
International Filing Date 11.06.2001
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • BIOWINDOW GENE DEVELOPMENT INC. SHANGHAI [CN]/[CN] (AllExceptUS)
  • MAO, Yumin [CN]/[CN] (UsOnly)
  • XIE, Yi [CN]/[CN] (UsOnly)
Inventors
  • MAO, Yumin
  • XIE, Yi
Agents
  • WATSON & BAND LAW OFFICES
Priority Data
00 1 16516.x14.06.2000CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) A NOVEL POLYPEPTIDE - HUMAN OXYSTEROL-BINDING PROTEIN 38.72 AND A POLYNUCLEOTIDE ENCODING THE SAME
(FR) NOUVEAU POLYPEPTIDE, PROTEINE HUMAINE DE LIAISON 38.72 AU STEROL DE TYPE OXYGENE, ET POLYNUCLEOTIDE CODANT CE POLYPEPTIDE
Abstract
(EN) The present invention discloses a novel polypeptide - human oxysterol-binding protein 38.72 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technique. The present invention also discloses methods of using the polypeptide in treatment of various disease, such as various disease associated with disturbance of cholesterol metabolism. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding human oxysterol-binding protein 38.72.
(FR) L'invention concerne un nouveau polypeptide, une protéine humaine de liaison 38.72 au stérol de type oxygène, et un polynucléotide codant ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment de toutes sortes de troubles du métabolisme du cholestérol. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant la protéine humaine de liaison 38.72 au stérol de type oxygène.
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