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1. WO2002002520 - COMPOUNDS TO TREAT ALZHEIMER'S DISEASE

Publication Number WO/2002/002520
Publication Date 10.01.2002
International Application No. PCT/US2001/021000
International Filing Date 02.07.2001
Chapter 2 Demand Filed 24.01.2002
IPC
C07C 215/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
215Compounds containing amino and hydroxy groups bound to the same carbon skeleton
02having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
22the carbon skeleton being unsaturated
28and containing six-membered aromatic rings
C07C 233/78 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
233Carboxylic acid amides
64having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
77having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
78with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
C07C 235/84 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
235Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
70having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
84with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
C07C 239/20 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
239Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
08Hydroxylamino compounds or their ethers or esters
20having oxygen atoms of hydroxylamino groups etherified
C07C 243/22 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
243Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
10Hydrazines
22having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
C07C 243/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
243Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
26with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
28to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
CPC
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C07C 215/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
215Compounds containing amino and hydroxy groups bound to the same carbon skeleton
02having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
22the carbon skeleton being unsaturated
28and containing six-membered aromatic rings
C07C 233/78
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
233Carboxylic acid amides
64having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
77having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
78with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
C07C 235/84
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
235Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
70having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
84with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
C07C 239/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
239Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
08Hydroxylamino compounds or their ethers or esters
20having oxygen atoms of hydroxylamino groups etherified
C07C 243/22
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
243Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
10Hydrazines
22having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
Applicants
  • ELAN PHARMACEUTICALS, INC. [US]/[US]
  • PHARMACIA & UPJOHN COMPANY [US]/[US]
Inventors
  • BECK, James, P.
  • GAILUNAS, Andrea
  • HOM, Roy
  • JAGODZINSKA, Barbara
  • JOHN, Varghese
  • MAILLAIRD, Michel
Agents
  • SARUSSI, Steven, J.
Priority Data
09/895,84329.06.2001US
60/215,32330.06.2000US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS TO TREAT ALZHEIMER'S DISEASE
(FR) COMPOSANTS UTILISES DANS LE TRAITEMENT DE LA MALADIE D'ALZHEIMER
Abstract
(EN) The present invention is disubstituted amines of formula (I) and disubstituted amines of formula (II) useful in treating Alzheimer's disease and other similar diseases.
(FR) L'invention concerne des amines disubstituées de formule (I) et des amines disubstituées de formule (II) utilisées dans le traitement de la maladie d'Alzheimer et d'autres affections similaires.
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