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1. (WO2002002517) ACYLSULFONAMIDE DERIVATIVES

Pub. No.:    WO/2002/002517    International Application No.:    PCT/JP2001/005626
Publication Date: Jan 10, 2002 International Filing Date: Jun 29, 2001
IPC: A61K 31/18
C07C 311/51
Applicants: AJINOMOTO CO.,INC.

IKAWA, Hiroshi

NISHIMURA, Masato

OKADA, Keiji

NAKAMURA, Takashi

KOJIMA, Kazuhiro

KOSONO, Hideki

Inventors: IKAWA, Hiroshi

NISHIMURA, Masato

OKADA, Keiji

NAKAMURA, Takashi

KOJIMA, Kazuhiro

KOSONO, Hideki

Title: ACYLSULFONAMIDE DERIVATIVES
Abstract:
Novel acylsulfonamide derivatives such as 4-(3-trifluoromethyl)phenylethyl-N-(2-(5-ketohexanoylamino)sulfonylphenyl)benzamide, 4-(3-trifluoromethyl)phenylethyl-N-(2-(2-propyloxyacetylamino)sulfonylphenyl)benzamide and analogs thereof (refer to the following general formula). These acylsulfonamide derivatives have a hypoglycemic effect comparable or even superior to the conventional hypoglycemics without showing such side effects as observed in glitazone compounds.