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1. (WO2002002172) DNA PALINDROME - OLIGOGUANYLIC ACID COMPOSITIONS AND USES THEREOF

Pub. No.:    WO/2002/002172    International Application No.:    PCT/US2001/020443
Publication Date: Jan 10, 2002 International Filing Date: Jun 27, 2001
IPC: C07H 21/00
Applicants: THOMAS JEFFERSON UNIVERSITY
Inventors: KAJI, Hideko
KAJI, Akira
YAMAMOTO, Saburo
Title: DNA PALINDROME - OLIGOGUANYLIC ACID COMPOSITIONS AND USES THEREOF
Abstract:
The present invention provides an oligonucleotide for stimulating an immune response in a mammal. The oligonucleotides of the invention are palindromic and flanked by up to 11 guanylic acid residues. The immune response is stimulated by administering the oligonucleotides of the invention and inducing the secretion of cytokines.