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1. (WO2002002144) MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/002144    International Application No.:    PCT/JP2001/005808
Publication Date: 10.01.2002 International Filing Date: 04.07.2001
Chapter 2 Demand Filed:    17.01.2002    
IPC:
A61K 38/08 (2006.01), A61K 38/09 (2006.01), A61K 45/06 (2006.01)
Applicants: TAKEDA CHEMICAL INDUSTRIES, LTD. [JP/JP]; 1-1, Doshomachi 4-chome Chuo-ku Osaka-shi Osaka 541-0045 (JP) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW only).
IGARI, Yasutaka [JP/JP]; (JP) (For US Only).
KAMEI, Shigeru [JP/JP]; (JP) (For US Only)
Inventors: IGARI, Yasutaka; (JP).
KAMEI, Shigeru; (JP)
Agent: TAKAHASHI, Shuichi; Osaka Plant of Takeda Chemical Industries, Ltd. 17-85, Jusohonmachi 2-chome Yodogawa-ku Osaka-shi Osaka 532-0024 (JP)
Priority Data:
2000-208253 05.07.2000 JP
Title (EN) MEDICINAL PREPARATIONS FOR TREATING SEX HORMONE-DEPENDENT DISEASES
(FR) PREPARATIONS MEDICINALES POUR LE TRAITEMENT DES MALADIES DEPENDANT DES HORMONES SEXUELLES
Abstract: front page image
(EN)Medicinal preparations for treating sex hormone-dependent diseases which comprise a combination of a compound having a luteinizing hormone-releasing hormone effect or its salt with a compound having a luteinizing hormone-releasing hormone antagonism or its salt for administering the compound having a luteinizing hormone-releasing hormone effect or its salt followed by the compound having a luteinizing hormone-releasing hormone antagonism or its salt. By using these preparations, the concentration of a sex hormone (for example, testosterone, LH, FSH, estrogen) can be quickly recovered after the medicable period of a compound having a luteinizing hormone-releasing hormone antagonism or its salt or a preparation containing the same (preferably a sustained-release preparation), which makes it possible to definitely determine the drug rest period in an intermittent treatment.
(FR)L'invention porte sur des préparations médicinales destinées à traiter des maladies dépendant des hormones sexuelles et comprenant une combinaison d'un composé ayant un effet de la lutéolibérine ou de son sel avec un composé ayant un antagonisme de la lutéolibérine ou son sel. Avec ces préparations, la concentration d'une hormone sexuelle (telle que la testostérone, LH, FSH, l'oestrogène) peut être rapidement récupérée après la période de médication d'un composé ayant un antagonisme de la lutéolibérine ou son sel ou une préparation contenant celui-ci (de préférence une préparation à libération prolongée), ce qui permet de déterminer rapidement la période de repos médicamenteuse au cours d'un traitement intermittent.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)