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Machine translation
1. (WO2002000872) COMPOSITIONS AND METHODS FOR TREATING OR DETECTING DEGENERATIVE DISEASES OF THE MOTOR NEURONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/000872    International Application No.:    PCT/FR2001/002058
Publication Date: 03.01.2002 International Filing Date: 28.06.2001
Chapter 2 Demand Filed:    24.12.2001    
IPC:
A61K 38/00 (2006.01), C12N 9/16 (2006.01)
Applicants: EXONHIT THERAPEUTICS SA [FR/FR]; 63-65, boulevard Masséna F-75013 Paris (FR) (For All Designated States Except US).
AÏT IKHLEF, Ali [FR/FR]; (FR) (For US Only).
RESINK, Annelies [NL/FR]; (FR) (For US Only).
SCHWEIGHOFFER, Fabien [FR/FR]; (FR) (For US Only)
Inventors: AÏT IKHLEF, Ali; (FR).
RESINK, Annelies; (FR).
SCHWEIGHOFFER, Fabien; (FR)
Agent: BECKER, Philippe; Cabinet Becker et Associes 35 rue des Mathurins F-75008 Paris (FR)
Priority Data:
00/08407 29.06.2000 FR
Title (EN) COMPOSITIONS AND METHODS FOR TREATING OR DETECTING DEGENERATIVE DISEASES OF THE MOTOR NEURONS
(FR) COMPOSITIONS ET METHODES POUR LE TRAITEMENT OU LA DETECTION DE PATHOLOGIES NEURODEGENERATIVES
Abstract: front page image
(EN)The invention concerns the field of biology, genetics and medicine. In particular, it concerns novel methods for detecting, characterising and/or treating (or managing) degenerative diseases of the motor neurons, in particular amyotrophic lateral sclerosis. The invention also concerns methods for identifying or screening compounds active in said pathologies. The invention further concerns compounds, genes, cells, plasmids or compositions useful for implementing said methods. The invention finally concerns the part played by calcineurin in said pathologies and its use as therapeutic, diagnostic or experimental target.
(FR)La présente invention concerne le domaine de la biologie, de la génétique et de la médecine. Elle concerne notamment de nouvelles méthodes pour la détection, la caractérisation et/ou le traitement (ou la prise en charge) de pathologies neurodégénératives, notamment de la sclérose latérale amyotrophique. L'invention concerne également des méthodes pour l'identification ou le screening de composés actifs dans ces pathologies. L'invention concerne également les composés, gènes, cellules, plasmides ou compositions utiles pour la mise en oeuvre des méthodes ci-dessus. L'invention décrit notamment le rôle de calcineurine dans ces pathologies et son utilisation comme cible thérapeutique, diagnostique ou expérimentale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)