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Machine translation
1. (WO2002000166) NEW COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2002/000166    International Application No.:    PCT/SE2001/001421
Publication Date: 03.01.2002 International Filing Date: 20.06.2001
Chapter 2 Demand Filed:    17.12.2001    
IPC:
C07D 401/12 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (For All Designated States Except US).
BERGMAN, Rolf [SE/SE]; (SE) (For US Only).
EEK, Arne [SE/SE]; (SE) (For US Only).
LINDBERG, Per [SE/SE]; (SE) (For US Only).
OLSSON, Lars-Inge [SE/SE]; (SE) (For US Only)
Inventors: BERGMAN, Rolf; (SE).
EEK, Arne; (SE).
LINDBERG, Per; (SE).
OLSSON, Lars-Inge; (SE)
Agent: ASTRAZENECA AB; Global Intellectual Property S-151 85 Södertälje (SE)
Priority Data:
0002476-0 30.06.2000 SE
Title (EN) NEW COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS
(FR) NOUVEAUX COMPOSES UTILES COMME AGENTS ANTIBACTERIENS
Abstract: front page image
(EN)The present invention relates to novel compounds of Formula I, and pharmaceutically acceptable salts thereof, as antibacterial agents. The compounds of the present invention are nitric oxide releasing derivatives of proton pump inhibitors (NO-releasing PPIs). In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above. The invention also relates to new intermediates for use in the preparation of the novel compounds. Additionally the present invention relates to co-administration of NO-releasing PPIs with other known medicaments.
(FR)L'invention concerne de nouveaux composés représentés par la formule I et des sels pharmaceutiquement acceptables de ceux-ci, utiles comme agents antibactériens. Ces composés sont des dérivés d'inhibiteurs de la pompe à protons qui libèrent du monoxyde d'azote (IPP à libération de NO). Dans d'autres aspects, l'invention concerne des applications thérapeutiques des composés décrits ; des procédés de préparation de ces nouveaux composés ; des compositions pharmaceutiques contenant comme principe actif au moins un composé de l'invention ou un sel pharmaceutiquement acceptable de celui-ci ; et l'utilisation de ces composés actifs dans la fabrication de médicaments. L'invention concerne également de nouveaux produits intermédiaires s'utilisant dans la préparation des nouveaux composés. De plus, l'invention concerne l'administration concomitante des IPP à libération de NO avec d'autres médicaments connus.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)