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Machine translation
1. (WO2001085795) TRIVALENT ANTIBODY CONSTRUCTS HAVING VARIABLE REGIONS THAT ARE STABILIZED BY DISULFIDE BRIDGES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/085795    International Application No.:    PCT/EP2001/005161
Publication Date: 15.11.2001 International Filing Date: 07.05.2001
Chapter 2 Demand Filed:    15.11.2001    
IPC:
C07K 16/00 (2006.01), C07K 16/46 (2006.01), C12N 15/62 (2006.01)
Applicants: UNIVERSITÄT HEIDELBERG [DE/DE]; Grabengasse 1 69117 Heidelberg (DE) (For All Designated States Except US).
DÜBEL, Stefan [DE/DE]; (DE) (For US Only).
SCHMIEDL, Andreas [DE/DE]; (DE) (For US Only)
Inventors: DÜBEL, Stefan; (DE).
SCHMIEDL, Andreas; (DE)
Agent: PERREY, Ralf; Müller-Boré & Partner Grafinger Strasse 2 81671 München (DE)
Priority Data:
100 21 678.1 05.05.2000 DE
Title (DE) TRIVALENTE ANTIKÖRPERKONSTRUKTE MIT DISULFID-BRÜCKEN STABILISIERTEN VARIABLEN REGIONEN
(EN) TRIVALENT ANTIBODY CONSTRUCTS HAVING VARIABLE REGIONS THAT ARE STABILIZED BY DISULFIDE BRIDGES
(FR) ANTICORPS DE RECOMBINAISON TRIVALENTS A REGIONS VARIABLES STABILISEES PAR DES PONTS DISULFURE
Abstract: front page image
(DE)Die vorliegende Erfindung betrifft rekombinante Antikörperkonstrukte, Verfahren zu deren Herstellung, pharmazeutische Zusammensetzungen und diagnostische Mittel, welche diese rekombinanten Antikörperkonstrukte enthalten, sowie die Verwendung dieser rekombinanten Antikörperkonstrukte zur Diagnose und Behandlung von Krebserkrankungen, Autoimmunerkrankungen, Allergien, immunologischen Überreaktionen, Infektionen oder Noxen.
(EN)The invention relates to recombinant antibody constructs, to methods for the production thereof, to pharmaceutical compositions and diagnostic agents, which contain these recombinant antibody constructs, as well as to the use of these recombinant antibody constructs for diagnosing and treating cancerous diseases, autoimmune diseases, allergies, immunological hyperreactions, infections or noxae.
(FR)Anticorps de recombinaison, procédé de fabrication desdits anticorps, compositions pharmaceutiques et moyens diagnostiques contenant ces anticorps de recombinaison, et utilisation de ces anticorps de recombinaison pour le diagnostic et le traitement de cancers, de maladies auto-immunes, d'allergies, d'hyperréactions immunologiques, d'infections ou de troubles pathologiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)