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1. (WO2001085685) HETEROCYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE GSK-3
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/085685    International Application No.:    PCT/GB2001/002100
Publication Date: 15.11.2001 International Filing Date: 11.05.2001
Chapter 2 Demand Filed:    01.11.2001    
IPC:
C07C 49/395 (2006.01), C07C 49/597 (2006.01), C07D 207/456 (2006.01), C07D 209/48 (2006.01), C07D 249/12 (2006.01), C07D 277/36 (2006.01), C07D 285/08 (2006.01), C07D 417/12 (2006.01)
Applicants: CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS [ES/ES]; Serrano, 113, E-28006 Madrid (ES) (For All Designated States Except US).
RUFFLES, Graham, Keith [GB/GB]; (GB) (SD only).
MARTINEZ GIL, Ana [ES/ES]; (ES) (For US Only).
CASTRO MORERA, Ana [ES/ES]; (ES) (For US Only).
PEREZ MARTIN, María Concepción [ES/ES]; (ES) (For US Only).
CASCON, Mercedes Alonso [ES/ES]; (ES) (For US Only).
DIAZ, Isabel, Dorronsoro [ES/ES]; (ES) (For US Only).
MORENO MUÑOZ, Francisco Jose [ES/ES]; (ES) (For US Only).
WANDOSELL, JURADO, Francisco [ES/ES]; (ES) (For US Only)
Inventors: MARTINEZ GIL, Ana; (ES).
CASTRO MORERA, Ana; (ES).
PEREZ MARTIN, María Concepción; (ES).
CASCON, Mercedes Alonso; (ES).
DIAZ, Isabel, Dorronsoro; (ES).
MORENO MUÑOZ, Francisco Jose; (ES).
WANDOSELL, JURADO, Francisco; (ES)
Agent: RUFFLES, Graham, Keith; Marks & Clerk, 57-60 Lincoln's Inn Fields, London WC2A 3LS (GB)
Priority Data:
p 200001185 11.05.2000 ES
0030284.4 12.12.2000 GB
Title (EN) HETEROCYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE GSK-3
(FR) INHIBITEURS HETEROCYCLIQUES DE LA GLYCOGENE SYNTHASE KINASE GSK-3
Abstract: front page image
(EN)Compounds of formula (I) where A, E, G, X, Y, and the bond --- take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arterosclerosis or restenosis.
(FR)L'invention concerne des composés représentés par la formule (I) dans laquelle A, E, G, X, Y, et la liaison --- ont des significations variées. Ces composés sont utiles pour la préparation de formulations pharmaceutiques destinées par exemple au traitement d'une maladie dans laquelle la GSK3 est impliquée, notamment la maladie d'Alzheimer ou le diabète non insulino-dépendant, ou les pathologies hyperprolifératives telles que cancers, displasies ou métaplasies tissulaires, psoriasis, artériosclérose ou resténose.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)