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1. (WO2001085173) ALKYLAMINE DERIVATIVES OF DIHYDROPYRIDINE NPY ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/085173    International Application No.:    PCT/US2001/015018
Publication Date: 15.11.2001 International Filing Date: 10.05.2001
Chapter 2 Demand Filed:    27.11.2001    
IPC:
C07D 211/90 (2006.01), C07D 401/12 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; Lawrenceville-Princeton Road P.O. Box 4000 Princeton, NJ 08543-4000 (US)
Inventors: POINDEXTER, Graham, S.; (US).
BRUCE, Marc; (US).
SIT, Sing-Yuen; (US).
MARTIN, Scott, W.; (US)
Agent: RYAN, Richard, P.; Bristol-Myers Squibb Company Lawrenceville-Princeton Road P.O. Box 4000 Princeton, NJ 08543-4000 (US)
Priority Data:
60/202,901 10.05.2000 US
Title (EN) ALKYLAMINE DERIVATIVES OF DIHYDROPYRIDINE NPY ANTAGONISTS
(FR) DERIVES D'ALKYLAMINE D'ANTAGONISTES DE DIHYDROPYRIDINE NPY
Abstract: front page image
(EN)A series of non-peptidergic antagonists of NPY have been synthesized and are comprises of amino and piperazine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (1) where X is CH or N. As antagonists of NPY-induced behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
(FR)Une série d'antagonistes non-peptidergiques de NPY ont été synthétisés et comprennent des dérivés de pipérazine de 4-phényl-1,4-dihydropyridines de formule (1) où X désigne CH ou N. En tant qu'antagonistes du comportement induit par NPY, ces composés sont considérés comme devant agir comme agents anorexiants efficaces pour la perte de poids et le traitement des troubles du comportement alimentaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)