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1. (WO2001083481) IMIDAZOPYRIDINE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/083481    International Application No.:    PCT/JP2001/003649
Publication Date: 08.11.2001 International Filing Date: 26.04.2001
Chapter 2 Demand Filed:    06.07.2001    
IPC:
C07D 471/04 (2006.01), C07D 487/04 (2006.01)
Applicants: YAMANOUCHI PHARMACEUTICAL CO., LTD. [JP/JP]; 3-11, Nihonbashi-Honcho 2-chome Chuo-ku, Tokyo 103-8411 (JP) (For All Designated States Except US).
LUDWIG INSTITUTE FOR CANCER RESEARCH [US/US]; 605, Third Avenue New York, NY 10158 (US) (For All Designated States Except US).
IMPERIAL CANCER RESEARCH TECHNOLOGY LTD. [GB/GB]; Sardinia House Sardinia Street, London WC2A 3NL (GB) (For All Designated States Except US).
HAYAKAWA, Masahiko [JP/JP]; (JP) (For US Only).
KAIZAWA, Hiroyuki [JP/JP]; (JP) (For US Only).
KAWAGUCHI, Ken-Ichi [JP/JP]; (JP) (For US Only).
MATSUDA, Koyo [JP/JP]; (JP) (For US Only).
ISHIKAWA, Noriko [JP/JP]; (JP) (For US Only).
KOIZUMI, Tomonobu [JP/JP]; (JP) (For US Only).
YAMANO, Mayumi [JP/JP]; (JP) (For US Only).
OKADA, Minoru [JP/JP]; (JP) (For US Only).
OHTA, Mitsuaki [JP/JP]; (JP) (For US Only)
Inventors: HAYAKAWA, Masahiko; (JP).
KAIZAWA, Hiroyuki; (JP).
KAWAGUCHI, Ken-Ichi; (JP).
MATSUDA, Koyo; (JP).
ISHIKAWA, Noriko; (JP).
KOIZUMI, Tomonobu; (JP).
YAMANO, Mayumi; (JP).
OKADA, Minoru; (JP).
OHTA, Mitsuaki; (JP)
Agent: NAGAI, Shozo; c/o Yamanouchi Pharmaceutical Co., Ltd. Patent Department 17-1, Hasune 3-chome Itabashi-ku, Tokyo 174-8612 (JP)
Priority Data:
2000-128295 27.04.2000 JP
Title (EN) IMIDAZOPYRIDINE DERIVATIVES
(FR) DERIVES D'IMIDAZOPYRIDINE
Abstract: front page image
(EN)Novel compounds are provided, which are useful as drugs, particularly anticancer drugs exhibiting phosphatidylinositol 3-kinase (PI3K) inhibiting activity. Novel 3-(imidazo[1,2-a]pyridin-3-yl) derivatives or salts thereof exhibit excellent inhibitory activities against PI3K and proliferation of cancer cells and are useful as PI3K inhibitors and anticancer drugs.
(FR)Nouveaux composés qui sont utiles en tant que médicaments, particulièrement en tant que médicaments contre le cancer, et qui possèdent une activité d'inhibition de la phosphatidylinositol 3-kinase (PI3K). Ces nouveaux dérivés 3-(imidazo[1,2-a]pyridin-3-yle) ou les sels desdits composés possèdent une excellente activité d'inhibition de la PI3K et de la prolifération de cellules cancéreuses, et sont utiles en tant qu'inhibiteurs de PI3K et en tant que médicaments contre le cancer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)