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1. (WO2001082966) COMBINATION THERAPY OF RESPIRATORY DISEASES USING ANTIBODIES AND ANTI-INFLAMMATORY AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/082966    International Application No.:    PCT/US2001/014193
Publication Date: 08.11.2001 International Filing Date: 03.05.2001
Chapter 2 Demand Filed:    30.11.2001    
IPC:
A61K 39/42 (2006.01), C07K 16/10 (2006.01)
Applicants: MEDIMMUNE, INC. [US/US]; 35 West Watkins Mill Road Gaithersburg, MD 20878 (US).
VIRION SYSTEMS, INC. [US/US]; Suite 100 9610 Medical Center Drive Rockville, MD 20850 (US)
Inventors: PRINCE, Gregory; (US).
JOHNSON, Leslie, S.; (US)
Agent: GRANT, Alan, J.; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein 6 Becker Farm Road Roseland, NJ 07068 (US)
Priority Data:
60/201,404 03.05.2000 US
Title (EN) COMBINATION THERAPY OF RESPIRATORY DISEASES USING ANTIBODIES AND ANTI-INFLAMMATORY AGENTS
(FR) POLYTHERAPIE POUR MALADIES RESPIRATOIRES, DANS LAQUELLE DES ANTICORPS ET DES AGENTS ANTI-INFLAMMATOIRES SONT UTILISES
Abstract: front page image
(EN)Therapeutically effective anti-viral compositions, useful especially against respiratory diseases caused or mediated by respiratory syncytial virus (RSV) are disclosed, wherein said compositions comprise at least one anti-RSV antibody, including high affinity antibodies, and an additional anti-inflammatory agent, especially corticosteroids, as well as anti-inflammatory antibodies, especially anti-interleukin-6. Also disclosed are methods of using such compositions to treat and/or prevent respiratory diseases. Such compositions may optionally contain other non-antibody anti-viral agents.
(FR)L'invention concerne des compositions anti-virales efficaces au plan thérapeutique, utiles notamment contre les maladies respiratoires induites ou médiées par le virus respiratoire syncytial (RS). Lesdites composition comprennent au moins un anticorps anti-virus RS, dont des anticorps d'affinité élevée, et un agent anti-inflammatoire supplémentaire, notamment des corticostéroïdes, ainsi que des anticorps anti-inflammatoires, notamment des anti-interleukine-6. L'invention porte également sur des procédés d'utilisation desdites compositions pour le traitement et/ou la prévention de maladies respiratoires. Lesdites compositions peuvent éventuellement contenir d'autres agents anti-viraux non-anticorpaux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)