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1. (WO2001081622) DIAGNOSIS OF DISEASES ASSOCIATED WITH DNA REPAIR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/081622    International Application No.:    PCT/EP2001/003972
Publication Date: 01.11.2001 International Filing Date: 06.04.2001
Chapter 2 Demand Filed:    28.09.2002    
IPC:
B01J 19/00 (2006.01), C07K 14/46 (2006.01), C07K 14/47 (2006.01), C07K 14/82 (2006.01), C12Q 1/68 (2006.01)
Applicants: EPIGENOMICS AG [DE/DE]; Kastanienallee 24, 10435 Berlin (DE) (For All Designated States Except US).
OLEK, Alexander [DE/DE]; (DE) (For US Only).
PIEPENBROCK, Christian [DE/DE]; (DE) (For US Only).
BERLIN, Kurt [DE/DE]; (DE) (For US Only)
Inventors: OLEK, Alexander; (DE).
PIEPENBROCK, Christian; (DE).
BERLIN, Kurt; (DE)
Agent: SCHOHE, Stefan; Boehmert & Boehmert, Pettenkoferstrasse 20-22, 80336 München (DE)
Priority Data:
100 19 058.8 06.04.2000 DE
100 19 173.8 07.04.2000 DE
100 32 529.7 30.06.2000 DE
100 43 826.1 01.09.2000 DE
Title (EN) DIAGNOSIS OF DISEASES ASSOCIATED WITH DNA REPAIR
(FR) DIAGNOSTIC DE MALADIES ASSOCIEES A LA REPARATION DE L'ADN
Abstract: front page image
(EN)The present invention relates to the chemically modified genomic sequences of genes associated with DNA repair, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genes associated with DNA repair which are directed against the sequence, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes associated with DNA repair.
(FR)L'invention concerne les séquences génomiques chimiquement modifiées de gènes associés à la réparation de l'ADN, ainsi que des oligonucléotides et/ou des oligomères PNA destinés à détecter l'état de méthylation de la cytosine de gènes associés à la réparation de l'ADN, qui sont dirigés contre la séquence. L'invention concerne également un procédé permettant de déterminer des paramètres génétiques et/ou épigénétiques de gènes associés à la réparation de l'ADN.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)