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1. (WO2001081372) VANCOMYCIN ANALOGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/081372    International Application No.:    PCT/US2001/011040
Publication Date: 01.11.2001 International Filing Date: 05.04.2001
Chapter 2 Demand Filed:    26.11.2001    
IPC:
A61K 38/00 (2006.01), C07K 9/00 (2006.01)
Applicants: THE TRUSTEES OF PRINCETON UNIVERSITY [US/US]; New South Building, 5th floor, Princeton, NJ 08544 (US)
Inventors: KAHNE, Daniel; (US).
WALKER, Suzanne; (US)
Agent: TSEVDOS, Estelle, J.; Kenyon & Kenyon, 1500 K Street, N.W., Suite 700, Washington, DC 20005 (US)
Priority Data:
60/199,382 25.04.2000 US
09/818,787 28.03.2001 US
Title (EN) VANCOMYCIN ANALOGS
(FR) ANALOGUES DE VANCOMYCINE
Abstract: front page image
(EN)Compounds that are vancomycin analogs bearing terminal carboxyl group modifications as well as modifications to the vancosamine nitrogen and, optionally, modifications to the C6 position of the glucose residue attached to the amino acid four of the vancomycin heptapeptide chain are disclosed. Methods of making the compounds and methods of using the compounds to treat a bacterial infection in a host are also disclosed.
(FR)L'invention concerne des composés sous forme d'analogues de vancomycine présentant des modifications du groupe carboxyle ainsi que des modifications de l'azote de vancosamine et, éventuellement, des modifications apportées à la position C6 du résidu de glucose fixé à l'acide aminé quatre de la chaîne heptapeptidique de la vancomycine. L'invention concerne également des méthodes de préparation de ces composés et des méthodes d'utilisation de ces composés pour traiter une infection bactérienne chez un hôte.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)