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Machine translation
1. (WO2001081355) COMBRETASTATIN A-1 PHOSPHATE AND COMBRETASTATIN B-1 PHOSPHATE PRODRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/081355    International Application No.:    PCT/US2001/013858
Publication Date: 01.11.2001 International Filing Date: 27.04.2001
Chapter 2 Demand Filed:    26.12.2001    
IPC:
C07C 255/43 (2006.01), C07D 213/82 (2006.01), C07D 217/20 (2006.01), C07D 295/027 (2006.01), C07D 453/04 (2006.01), C07F 9/12 (2006.01)
Applicants: ARIZONA BOARD OF REGENTS, a body corporate of THE STATE OF ARIZONA,acting for and on behalf of ARIZONA STATE UNIVERSITY [US/US]; Tempe, AZ 85287 (US) (For All Designated States Except US).
PETTIT, George, R. [US/US]; (US) (For US Only).
LIPPERT, John, W., III [US/US]; (US) (For US Only)
Inventors: PETTIT, George, R.; (US).
LIPPERT, John, W., III; (US)
Agent: MYBECK, Richard, R.; PO Box 5540 Scottsdale, AZ 85261-5540 (US)
Priority Data:
60/200,395 27.04.2000 US
Title (EN) COMBRETASTATIN A-1 PHOSPHATE AND COMBRETASTATIN B-1 PHOSPHATE PRODRUGS
(FR) PROMEDICAMENTS A BASE DE COMBRETASTATINE A-1 PHOSPHATE ET DE COMBRETASTATINE B-1 PHOSPHATE
Abstract: front page image
(EN)The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugs and the utilization of those prodrugs in the treatment of neoplastic diseases. The prodrugs described herein have the structure: Combretastin A-1 Phosphate Prodrug (I) and Combretastin B-1 Phosphate Prodrug (II).
(FR)L'invention concerne des synthèses et des analyses de promédicaments à base de combretastatine A1-phosphate et de promédicaments à base de combretastatine B1-phosphate, et l'utilisation de ces promédicaments pour traiter les maladies néoplasiques. Les promédicaments décrits dans cette invention présentent la structure suivante: (I) promédicament à base de combretastatine A-1 phosphate (II) promédicament à base de combretastatine B-1 phosphate.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR).
Publication Language: English (EN)
Filing Language: English (EN)