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Machine translation
1. (WO2001081337) INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/081337    International Application No.:    PCT/GB2001/001875
Publication Date: 01.11.2001 International Filing Date: 26.04.2001
Chapter 2 Demand Filed:    12.11.2001    
IPC:
C07D 401/12 (2006.01), C07D 403/12 (2006.01), C07D 417/12 (2006.01)
Applicants: FERRING B.V. [NL/NL]; Polaris Avenue 144 NL-2132 JX Hoofddorp (NL) (For All Designated States Except US).
EVANS, David, Michael [GB/GB]; (GB) (For US Only).
PITT, Gary, Robert, William [GB/GB]; (GB) (For US Only)
Inventors: EVANS, David, Michael; (GB).
PITT, Gary, Robert, William; (GB)
Agent: GEERING, Keith, Edwin; Reddie & Grose 16 Theobalds Road London WC1X 8PL (GB)
Priority Data:
0010188.1 26.04.2000 GB
Title (EN) INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
(FR) INHIBITEURS DE DIPEPTIDYL PEPTIDASE IV
Abstract: front page image
(EN)Compounds according to formula (1), wherein R?1¿ is H or CN, X?1¿ is S, O, SO¿2? or CH¿2?, X?2¿ is CO, CH¿2? or a covalent bond, Het is a nitrogen-containing heterocycle and n is 1-5 are new. The compounds of the invention are inhibitors of dipeptidyl peptidase IV. Pharmaceutical compositions of the compounds of the invention, or pharmaceutically acceptable salts thereof, are useful in the treatment of, inter alia, type 2 diabetes.
(FR)L'invention concerne de nouveaux composés de formule générale (1), dans laquelle R?1¿ représente H ou CN, X?1¿ représente S, O, SO¿2? ou CH¿2?, X?2¿ représente CO, CH¿2? ou une liaison covalente, Het représente un hétérocycle contenant de l'azote et n est compris entre 1 et 5, lesdits composés étant des inhibiteurs de la dipeptidyl peptidase IV. Cette invention concerne aussi des compositions pharmaceutiques renfermant ces composés ou des sels correspondants acceptables sur le plan pharmaceutique, utilisés dans le traitement notamment de diabètes de type 2.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)