WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2001080835) PROCESS FOR PRODUCING MICROSPHERE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/080835    International Application No.:    PCT/JP2001/003446
Publication Date: 01.11.2001 International Filing Date: 23.04.2001
Chapter 2 Demand Filed:    19.06.2001    
IPC:
A61K 9/50 (2006.01), A61K 47/34 (2006.01), B01J 13/12 (2006.01)
Applicants: TANABE SEIYAKU CO., LTD. [JP/JP]; 2-10, Dosho-machi 3-chome, Chuo-ku, Osaka-shi, Osaka 541-8505 (JP) (For All Designated States Except US).
SUZUKI, Takehiko [JP/JP]; (JP) (For US Only).
KITAZAWA, Takeo [JP/JP]; (JP) (For US Only).
MATSUMOTO, Akihiro [JP/JP]; (JP) (For US Only).
SUZUKI, Akira [JP/JP]; (JP) (For US Only)
Inventors: SUZUKI, Takehiko; (JP).
KITAZAWA, Takeo; (JP).
MATSUMOTO, Akihiro; (JP).
SUZUKI, Akira; (JP)
Agent: AOYAMA, Tamotsu; Aoyama & Partners, IMP Building, 3-7, Shiromi 1-chome, Chuo-ku, Osaka-shi, Osaka 540-0001 (JP)
Priority Data:
2000-122469 24.04.2000 JP
Title (EN) PROCESS FOR PRODUCING MICROSPHERE
(FR) PROCEDE DE PRODUCTION DE MICROSPHERES
Abstract: front page image
(EN)A process for producing microspheres, characterized by: adding a polymer solution comprising a drug, an in vivo degradable polymer, and a water-miscible good solvent (solvent (A)) for the polymer to a homogeneous liquid mixture comprising a solvent (solvent (B)) which is a poor solvent for the polymer and is miscible with the solvent (A) and a solvent (solvent (C)) which is a poor solvent for the polymer and is immiscible with the solvent (A); emulsifying the resultant mixture to prepare an emulsion in which the polymer solution forms a dispersed phase and the homogeneous liquid mixture forms a continuous phase; and removing the solvent (A) from the dispersed phase.
(FR)L'invention concerne un procédé de production de microsphères, qui consiste à ajouter une solution polymère comprenant un médicament, un polymère dégradable in vivo, et un bon solvant hydrosoluble (solvant (A)) pour le polymère à un mélange liquide homogène comprenant un solvant (solvant (B)) qui est un mauvais solvant pour le polymère et est miscible avec le solvant (A) et un solvant (solvant (C)) qui est un mauvais solvant pour le polymère et est non miscible avec le solvant (A); à émulsionner le mélange résultant afin de préparer une émulsion dans laquelle la solution polymère forme une phase dispersée et le mélange liquide homogène forme une phase continue; et à éliminer le solvant (A) de la phase dispersée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)