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1. (WO2001072123) METHODS FOR INCREASING A CYTOTOXIC T LYMPHOCYTE RESPONSE IN VIVO
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2001/072123 International Application No.: PCT/US2001/010118
Publication Date: 04.10.2001 International Filing Date: 28.03.2001
Chapter 2 Demand Filed: 03.08.2001
IPC:
A61K 39/00 (2006.01) ,A61K 39/21 (2006.01) ,A61K 39/385 (2006.01) ,A61K 39/39 (2006.01) ,C12Q 1/70 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
21
Retroviridae, e.g. equine infectious anemia virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
385
Haptens or antigens, bound to carriers
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
70
involving virus or bacteriophage
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th floor Oakland, CA 94607-5200, US (AllExceptUS)
DEPARTMENT OF VETERANS AFFAIRS [US/US]; Office of the General Counsel Washington, DC 20420, US (AllExceptUS)
RAZ, Eyal [IL/US]; US (UsOnly)
CHO, Hearn, Jay [US/US]; US (UsOnly)
RICHMAN, Douglas, D. [US/US]; US (UsOnly)
HORNER, Anthony, A. [--/US]; US (UsOnly)
Inventors:
RAZ, Eyal; US
CHO, Hearn, Jay; US
RICHMAN, Douglas, D.; US
HORNER, Anthony, A.; US
Agent:
FRANCIS, Carol, L.; Bozicevic, Field & Francis LLP Suite 200 200 Middlefield Road Menlo Park, CA 94025, US
Priority Data:
60/192,53728.03.2000US
60/203,56711.05.2000US
60/215,89505.07.2000US
Title (EN) METHODS FOR INCREASING A CYTOTOXIC T LYMPHOCYTE RESPONSE IN VIVO
(FR) PROCEDES CONÇU POUR AUGMENTER UNE REACTION DE LYMPHOCYTES T CYTOTOXIQUES IN VIVO
Abstract:
(EN) The invention provides methods for T helper-independent activation of an antigen-specific cytotoxic T lymphocyte response in an individual. The methods generally involve administering to an individual an immunostimulatory nucleic acid molecule in an amount effective to increase an antigen-specific CTL response in the individual. The invention further provides methods for increasing chemokine secretion, which can block HIV infection.
(FR) L'invention concerne des procédés d'activation indépendante de T auxiliaires d'une réaction de lymphocytes T cytotoxiques à spécificité antigénique chez un individu. Ces procédés consistent d'ordinaire à administrer à un individu une molécule d'acide nucléique immunostimulateur en dose efficace de façon à augmenter une réaction de lymphocytes T cytotoxiques à spécificité antigénique chez cet individu. L'invention concerne en outre des procédés destinés à augmenter la sécrétion de la chimiokine capable de bloquer l'infection du VIH.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)