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1. WO2001062228 - METHOD FOR TRANSDERMAL OR INTRADERMAL DELIVERY OF MOLECULES

Publication Number WO/2001/062228
Publication Date 30.08.2001
International Application No. PCT/US2001/005997
International Filing Date 26.02.2001
Chapter 2 Demand Filed 24.07.2001
IPC
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/127 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61N 1/32 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
CPC
A61K 9/0009
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
0009involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
A61K 9/127
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61N 1/0424
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
0416Anode and cathode
0424Shape of the electrode
A61N 1/044
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
0432Anode and cathode
044Shape of the electrode
A61N 1/306
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
20continuous direct currents
30Apparatus for iontophoresis, ; i.e. transfer of media in ionic state by an electromotoric force into the body; , or cataphoresis
303Constructional details
306Arrangements where at least part of the apparatus is introduced into the body
A61N 1/325
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
325for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Applicants
  • HEALTH RESEARCH, INC. [US]/[US] (AllExceptUS)
  • GENETRONICS, INC. [US]/[US] (AllExceptUS)
  • SEN, Arindam [IN]/[US] (UsOnly)
  • HUI, Sek, Wen [US]/[US] (UsOnly)
  • ZHAO, Ya, Li [US]/[US] (UsOnly)
  • ZHANG, Lei [CN]/[US] (UsOnly)
Inventors
  • SEN, Arindam
  • HUI, Sek, Wen
  • ZHAO, Ya, Li
  • ZHANG, Lei
Agents
  • KADLE, Ranjana
Priority Data
60/184,91825.02.2000US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR TRANSDERMAL OR INTRADERMAL DELIVERY OF MOLECULES
(FR) PROCEDE D'ADMINISTRATION TRANSDERMIQUE OU INTRADERMIQUE DE MOLECULES
Abstract
(EN) The present invention provides a method for transdermal delivery of molecules. The method comprises the application of electrical pulses concurrently or sequentially with application of the molecules and a lipid composition comprising negatively charged liposomal compositions. The liposomal components are used to enhance permeability of the target site for delivery of the molecule.
(FR) La présente invention se rapporte à un procédé d'administration transdermique de molécules. Ledit procédé consiste à appliquer des impulsions électriques simultanément ou séquentiellement à l'application des molécules et d'une composition lipidique comportant des compositions liposomales chargées négativement. Les composants liposomaux sont utilisés pour accroître la perméabilité du site cible en vue de l'administration de la molécule.
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