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1. WO2001059153 - METHOD FOR IDENTIFYING SUBSTANCES WHICH MODULATE THE ACTIVITY OF HYPERPOLARISATION-ACTIVATED CATION CHANNELS

Publication Number WO/2001/059153
Publication Date 16.08.2001
International Application No. PCT/EP2001/000755
International Filing Date 24.01.2001
Chapter 2 Demand Filed 31.08.2001
IPC
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
CPC
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
C12N 2503/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2503Use of cells in diagnostics
G01N 2500/00
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2500Screening for compounds of potential therapeutic value
G01N 33/6872
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Applicants
  • AVENTIS PHARMA DEUTSCHLAND GMBH [DE]/[DE]
Inventors
  • JANSEN, Hans-Willi
  • BRÜGGEMANN, Andrea
  • HEITSCH, Holger
  • GÖGELEIN, Heinz
Priority Data
100 06 309.812.02.2000DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) VERFAHREN ZUR IDENTIFIZIERUNG VON SUBSTANZEN, DIE DIE AKTIVITÄT VON HYPERPOLARISATIONS-AKTIVIERTEN KATIONEN-KANÄLEN MODULIEREN
(EN) METHOD FOR IDENTIFYING SUBSTANCES WHICH MODULATE THE ACTIVITY OF HYPERPOLARISATION-ACTIVATED CATION CHANNELS
(FR) PROCEDE D'IDENTIFICATION DE SUBSTANCES QUI MODULENT L'ACTIVITE DE CANAUX DE CATIONS ACTIVES PAR HYPOLARISATION
Abstract
(DE)
Gegenstand der vorliegenden Erfindung ist ein Verfahren zur Identifizierung von Substanzen, die die Aktivität von hyperpolarisations-aktivierten Kationen-Kanälen modulieren und die Verwendung des Verfahrens.
(EN)
The invention relates to a method for identifying substances which modify the activity of hyperpolarisation-activated cation-channels and to the use of this method.
(FR)
La présente invention concerne un procédé d'identification de substances qui modulent l'activité de canaux de cations activés par hyperpolarisation. L'invention concerne également l'utilisation de ce procédé.
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