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1. WO2001057005 - 1,3,4-OXADIAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME

Publication Number WO/2001/057005
Publication Date 09.08.2001
International Application No. PCT/JP2001/000742
International Filing Date 02.02.2001
Chapter 2 Demand Filed 09.08.2001
IPC
C07D 271/10 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
271Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02not condensed with other rings
101,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
CPC
C07D 271/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
271Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02not condensed with other rings
101,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
Applicants
  • ONO PHARMACEUTICAL CO., LTD. [JP]/[JP] (AllExceptUS)
  • SUGIURA, Tsuneyuki [JP]/[JP] (UsOnly)
  • MIYAZAKI, Toru [JP]/[JP] (UsOnly)
  • HORIUCHI, Toshihide [JP]/[JP] (UsOnly)
Inventors
  • SUGIURA, Tsuneyuki
  • MIYAZAKI, Toru
  • HORIUCHI, Toshihide
Agents
  • OHIE, Kunihisa
Priority Data
2000-2671803.02.2000JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) 1,3,4-OXADIAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
(FR) DERIVES DE 1,3,4-OXADIAZOLE ET LEUR PROCEDE DE PRODUCTION
Abstract
(EN) A process for producing 1,3,4-oxadiazole derivatives represented by the general formulae (I) and (III) (wherein the symbols have the same meanings as in the description); and the novel 1,3,4-oxadiazole derivative represented by the general formula (I). By the process, a compound represented by the general formula (III), which is an intermediate for a 1,3,4-oxadiazole derivative useful as a medicine (elastase inhibitor), can be efficiently produced via a novel intermediate (the compound represented by the general formula (I)).
(FR) L'invention concerne un procédé destiné à produire des dérivés de 1,3,4-oxadiazole représentés par les formules générales (I) et (III), dans lesquelles les symboles ont la même signification que dans la description, ainsi que le nouveau dérivé de 1,3,4-oxadiazole représenté par la formule générale (I). Ce procédé permet de produire efficacement un composé représenté par la formule générale (III), à savoir un intermédiaire pour un dérivé de 1,3,4-oxadiazole utilisé comme médicament (inhibiteur de l'élastase), au moyen d'un nouvel intermédiaire (le composé représenté par la formule générale (I)).
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