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1. WO2001055403 - A NOVEL POLYPEPTIDE, A HUMAN HELIX-DESTABILIZING ENZYME C20 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE

Publication Number WO/2001/055403
Publication Date 02.08.2001
International Application No. PCT/CN2001/000079
International Filing Date 21.01.2001
Chapter 2 Demand Filed 20.08.2001
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • BIODOOR GENE TECHNOLOGY LTD. SHANGHAI [CN]/[CN] (AllExceptUS)
  • MAO, Yumin [CN]/[CN] (UsOnly)
  • XIE, Yi [CN]/[CN] (UsOnly)
Inventors
  • MAO, Yumin
  • XIE, Yi
Agents
  • WATSON & BAND LAW OFFICES
Priority Data
00 1 11591.X28.01.2000CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) A NOVEL POLYPEPTIDE, A HUMAN HELIX-DESTABILIZING ENZYME C20 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
(FR) NOUVEAU POLYPEPTIDE, HELICASE HUMAINE C20, ET POLYNUCLEOTIDE CODANT POUR CE POLYPEPTIDE
Abstract
(EN) The present invention discloses a novel polypeptide, a human helix-destabilizing enzyme C20, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumor, hemopathy, HIV infection, immunological diseases, and various inflammation etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel human helix-destabilising enzyme C20.
(FR) L'invention concerne un nouveau polypeptide, une hélicase humaine C20, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour l'hélicase humaine C20.
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