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1. WO2001040264 - PEPTIDE ANTIGENS

Publication Number WO/2001/040264
Publication Date 07.06.2001
International Application No. PCT/US2000/033124
International Filing Date 06.12.2000
Chapter 2 Demand Filed 05.07.2001
IPC
A01K 67/027 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
A61K 38/11 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
11Oxytocins; Vasopressins; Related peptides
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/35 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
35Allergens
A61K 39/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
35Allergens
36from pollen
A61K 39/38 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
38Antigens from snakes
CPC
A01K 67/027
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
A61K 2039/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
53DNA (RNA) vaccination
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
35Allergens
A61K 39/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
35Allergens
36from pollen
Applicants
  • PANACEA PHARMACEUTICALS, LLC. [US]/[US]
  • UNIVERSITY OF ARKANSAS [US]/[US]
  • MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK [US]/[US]
Inventors
  • BANNON, Gary, A.
  • BURKS, Wesley, A.
  • CAPLAN, Michael, J.
  • SAMPSON, Hugh
  • SOSIN, Howard
Agents
  • JARRELL, Brenda, Herschbach
Priority Data
09/455,29406.12.1999US
60/213,76523.06.2000US
60/235,79727.09.2000US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PEPTIDE ANTIGENS
(FR) ANTIGENES PEPTIDIQUES
Abstract
(EN) The present invention provides compositions and methods for reducing the severity and/or number of allergic symptoms in individuals sensitive to one or more antigens. In general, the inventive compositions comprise fragments of antigens and are characterized by a reduced ability to bind to anti-antigen IgE. Preferred compositions comprise overlapping fragments that together represent substantially all of the structural features of the relevant antigen except that one or more IgE binding sites may be omitted. Particularly preferred compositions comprise fragments of anaphylactic antigens, especially food antigens such as peanut antigens or shellfish antigens.
(FR) L'invention concerne des compositions et des procédés destinés à réduire la sévérité et/ou le nombre de symtômes allergiques chez des individus sensibles à un ou plusieurs antigènes. De façon générale, les compositions selon l'invention comprennent des fragments d'antigènes et sont caractérisées par une aptitude réduite à se lier à un anti-antigène IgE. Les compositions préférées comprennent des fragments de recouvrement représentant conjointement sensiblement la totalité des caractéristiques structurelles de l'antigène concerné, à l'exception du fait qu'un ou plusieurs site de liaison IgE peuvent être omis. Des compositions particulièrement préférées comprennent des fragments d'antigènes anaphylactiques, notamment des antigènes d'aliments, tels que des antigènes de cacahouètes ou des antigènes de coquillages et crustacés.
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