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1. (WO2001038533) G PROTEIN-COUPLED RECEPTOR-LIKE RECEPTORS AND MODULATORS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/038533    International Application No.:    PCT/US2000/032225
Publication Date: 31.05.2001 International Filing Date: 24.11.2000
Chapter 2 Demand Filed:    22.06.2001    
IPC:
C07K 14/705 (2006.01)
Applicants: PHARMACIA & UPJOHN COMPANY [US/US]; 301 Henrietta Street, Kalamazoo, MI 49007 (US) (For All Designated States Except US).
LOWERY, David, E. [US/US]; (US) (For US Only).
GEARY, Timothy, G. [US/US]; (US) (For US Only).
KUBIAK, Teresa, M. [US/US]; (US) (For US Only).
LARSEN, Martha, J. [US/US]; (US) (For US Only)
Inventors: LOWERY, David, E.; (US).
GEARY, Timothy, G.; (US).
KUBIAK, Teresa, M.; (US).
LARSEN, Martha, J.; (US)
Agent: MERKEL, William, K.; Marshall, O'Toole, Gerstein, Murray & Borun, 6300 Sears Tower, 233 South Wacker Drive, Chicago, IL 60606-6402 (US)
Priority Data:
60/167,523 24.11.1999 US
Title (EN) G PROTEIN-COUPLED RECEPTOR-LIKE RECEPTORS AND MODULATORS THEREOF
(FR) RECEPTEURS SIMILAIRES AUX RECEPTEURS COUPLES AUX PROTEINES G ET LEURS MODULATEURS
Abstract: front page image
(EN)The invention provides neuropeptide ligands, G protein-coupled receptors and methods of screening for modulators of receptor activity. Identified modulators including neuropeptide ligand mimetics, are useful as biostatic and biocidal agents of varying scope, ranging from lethal activity restricted to particular invertebrate parasites to broad spectrum invertebrate parasiticides active on a wide range of invertebrates, including helminths and insects.
(FR)L'invention concerne des ligands de neuropeptides, des récepteurs couplés aux protéines G et des procédés pour cribler les modulateurs de l'activité des récepteurs. Les modulateurs identifiés, qui comprennent des mimétismes de ligands de neuropeptides, sont utiles en tant qu'agents biostatiques et biocidaux de portée différente allant de l'activité létale limitée aux parasites invertébrés particuliers jusqu'aux parasiticides dirigés contre les invertébrés à spectre large, qui agissent sur une gamme étendue d'invertébrés, y compris les helminthes et les insectes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)