Search International and National Patent Collections

1. (WO2001038487) MOUSE ASPARTIC SECRETASE-1 (mASP1)

Pub. No.:    WO/2001/038487    International Application No.:    PCT/US2000/032059
Publication Date: Fri Jun 01 01:59:59 CEST 2001 International Filing Date: Thu Nov 23 00:59:59 CET 2000
IPC: A61K 38/00
C12N 9/64
Applicants: SMITHKLINE BEECHAM CORPORATION
SMITHKLINE BEECHAM PLC
Inventors: ZHU, Yuan
LI, Xiaotong
POWELL, David, J.
CHRISTIE, Gary
Title: MOUSE ASPARTIC SECRETASE-1 (mASP1)
Abstract:
Mouse mASP1 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds that either agonize or antagonize mouse mASP1. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: Alzheimer's disease, cancer, and prohormone processing.